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CG8441 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36792, updated on 9-Dec-2024

Summary

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Official Symbol
CG8441provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034086
Locus tag
Dmel_CG8441
See related
AllianceGenome:FB:FBgn0034086
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8441
Summary
Predicted to enable double-stranded RNA binding activity; protein kinase binding activity; and protein kinase inhibitor activity. Predicted to be active in nucleolus. Is expressed in organism. Orthologous to human PRKRIP1 (PRKR interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG8441 in Genome Data Viewer
Location:
52F5-52F5; 2-78 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (16185122..16186506, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12072627..12074011, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Protein tyrosine phosphatase 52F Neighboring gene Lissencephaly-1 Neighboring gene clueless Neighboring gene calypso Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In Vivo RNAi-Based Screens: Studies in Model Organisms. Yamamoto-Hino M, et al. Genes (Basel), 2013 Nov 25. PMID 24705267, Free PMC Article
  2. A genome-wide RNAi screen identifies regulators of cholesterol-modified hedgehog secretion in Drosophila. Aikin R, et al. PLoS One, 2012. PMID 22432040, Free PMC Article
  3. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article
  4. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897
  5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables double-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein kinase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8441-PA
CG8441-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    16185122..16186506 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259433.1 → NP_001246362.1  uncharacterized protein Dmel_CG8441, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246362.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K1V1
    Conserved Domains (1) summary
    pfam06658
    Location:58 → 194
    DUF1168; Protein of unknown function (DUF1168)

  2. NM_137250.4 → NP_611094.1  uncharacterized protein Dmel_CG8441, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611094.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K1V1
    Related
    FBpp0086385
    Conserved Domains (1) summary
    pfam06658
    Location:58 → 194
    DUF1168; Protein of unknown function (DUF1168)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K1V1 Q7K1V1

Gene LinkOut

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