CG9313 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG9313provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0034566
Locus tag: Dmel_CG9313
See related: AllianceGenome:FB:FBgn0034566
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Dmel\CG9313
Summary: Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Involved in sensory perception of sound. Predicted to be part of outer dynein arm. Is expressed in Johnston organ neurons; chordotonal neurons; spermatogonium; and spermatozoon. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 1. Orthologous to human DNAI1 (dynein axonemal intermediate chain 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 57B5-57B5; 2-92 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (20978901..20984043)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (16866406..16871548)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables dynein heavy chain binding	IBA Inferred from Biological aspect of Ancestor more info
enables dynein light chain binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cilium movement	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium movement	ISS Inferred from Sequence or Structural Similarity more info
involved_in outer dynein arm assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in sensory perception of sound	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of outer dynein arm	IBA Inferred from Biological aspect of Ancestor more info
part_of outer dynein arm	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: uncharacterized protein

Names: CG9313-PA; CG9313-PB; CG9313-PC; dynein

NP_001286656.1

unusual splice

NP_611530.5

unusual splice

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033778.4 Reference assembly

Range

20978901..20984043

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001299727.1 → NP_001286656.1 uncharacterized protein Dmel_CG9313, isoform C [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001286656.1

Status: REVIEWED

UniProtKB/TrEMBL

Q7KVQ2, Q8MSJ9, Q9W2P3

Conserved Domains (3) summary

COG2319
Location:352 → 705

WD40; WD40 repeat [General function prediction only]

sd00039
Location:361 → 411

7WD40; WD40 repeat [structural motif]

cl02567
Location:412 → 639

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001299728.1 → NP_001286657.1 uncharacterized protein Dmel_CG9313, isoform B [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001286657.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A0B4LG18

Conserved Domains (3) summary

COG2319
Location:353 → 706

WD40; WD40 repeat [General function prediction only]

sd00039
Location:362 → 412

7WD40; WD40 repeat [structural motif]

cl02567
Location:413 → 640

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_137686.6 → NP_611530.5 uncharacterized protein Dmel_CG9313, isoform A [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_611530.5

Status: REVIEWED

UniProtKB/TrEMBL

Q7KVQ2, Q8MSJ9, Q9W2P3

Conserved Domains (3) summary

COG2319
Location:352 → 705

WD40; WD40 repeat [General function prediction only]

sd00039
Location:361 → 411

7WD40; WD40 repeat [structural motif]

cl02567
Location:412 → 639

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...