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SGMS1 sphingomyelin synthase 1 [ Gallus gallus (chicken) ]

Gene ID: 378907, updated on 3-Dec-2024

Summary

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Symbol
SGMS1provided by CGNC
Full Name
sphingomyelin synthase 1provided by CGNC
Primary source
CGNC:2707
See related
Ensembl:ENSGALG00010022771
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
MOB; TMEM23
Orthologs
human mouse all
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Genomic context

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See SGMS1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
20
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (10381065..10477607)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (10265042..10361589)

Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124418077 Neighboring gene 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Neighboring gene uncharacterized LOC121111165 Neighboring gene multiple inositol-polyphosphate phosphatase 1 Neighboring gene neutral ceramidase-like Neighboring gene N-acylsphingosine amidohydrolase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular cloning, sequence characterization, and tissue expression analysis of chicken sphingomyelin synthase 1 (SMS1). Man C, et al. Mol Cell Biochem, 2011 Nov. PMID 21647613
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ceramide cholinephosphotransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sphingomyelin synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingomyelin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylcholine:ceramide cholinephosphotransferase 1
Names
protein Mob
transmembrane protein 23
NP_989721.2
XP_015134154.1
XP_015134157.1
XP_015134158.1
XP_015134159.1
XP_015134160.1
XP_025007230.1
XP_025007231.1
XP_025007232.1
XP_025007234.1
XP_040558160.1
XP_040558161.1
XP_040558162.1
XP_040558164.1
XP_046775765.1
XP_046775766.1
XP_046775767.1
XP_046775768.1
XP_046775769.1
XP_046775770.1
XP_046775771.1
XP_046775772.1
XP_046775773.1
XP_046775774.1
XP_046775775.1
XP_046775776.1
XP_046775777.1
XP_046775778.1
XP_046775779.1
XP_046775780.1
XP_046775781.1
XP_046775782.1
XP_046775783.1
XP_046775784.1
XP_046775785.1
XP_046775786.1
XP_046775787.1
XP_046798655.1
XP_046798657.1
XP_046798658.1
XP_046798659.1
XP_046798660.1
XP_046798661.1
XP_046798662.1
XP_046798663.1
XP_046798664.1
XP_046798665.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204390.3 → NP_989721.2  phosphatidylcholine:ceramide cholinephosphotransferase 1

    See identical proteins and their annotated locations for NP_989721.2

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000227
    UniProtKB/TrEMBL
    F1DS94
    Related
    ENSGALP00010033517.1, ENSGALT00010055360.1
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    10381065..10477607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040702227.2 → XP_040558161.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  2. XM_040702226.2 → XP_040558160.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  3. XM_025151462.3 → XP_025007230.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  4. XM_046942709.1 → XP_046798665.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  5. XM_046942699.1 → XP_046798655.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  6. XM_015278668.4 → XP_015134154.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  7. XM_015278674.4 → XP_015134160.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  8. XM_046942701.1 → XP_046798657.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  9. XM_046942702.1 → XP_046798658.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  10. XM_046942706.1 → XP_046798662.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  11. XM_046942708.1 → XP_046798664.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  12. XM_046942704.1 → XP_046798660.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  13. XM_025151464.3 → XP_025007232.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  14. XM_046942703.1 → XP_046798659.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  15. XM_040702228.2 → XP_040558162.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Related
    ENSGALP00010033512.1, ENSGALT00010055355.1
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  16. XM_046942705.1 → XP_046798661.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  17. XM_025151463.3 → XP_025007231.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  18. XM_015278673.4 → XP_015134159.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  19. XM_046942707.1 → XP_046798663.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  20. XM_025151466.3 → XP_025007234.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  21. XM_015278671.4 → XP_015134157.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  22. XM_015278672.4 → XP_015134158.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

  23. XM_040702230.2 → XP_040558164.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
    Conserved Domains (2) summary
    cd09514
    Location:1 → 72
    SAM_SGMS1; SAM domain of sphingomyelin synthase
    pfam14360
    Location:276 → 349
    PAP2_C; PAP2 superfamily C-terminal

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    10265042..10361589
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046919816.1 → XP_046775772.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  2. XM_046919812.1 → XP_046775768.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  3. XM_046919830.1 → XP_046775786.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  4. XM_046919831.1 → XP_046775787.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  5. XM_046919810.1 → XP_046775766.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  6. XM_046919809.1 → XP_046775765.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  7. XM_046919821.1 → XP_046775777.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  8. XM_046919814.1 → XP_046775770.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  9. XM_046919815.1 → XP_046775771.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  10. XM_046919827.1 → XP_046775783.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  11. XM_046919829.1 → XP_046775785.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  12. XM_046919818.1 → XP_046775774.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  13. XM_046919822.1 → XP_046775778.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  14. XM_046919817.1 → XP_046775773.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  15. XM_046919823.1 → XP_046775779.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  16. XM_046919825.1 → XP_046775781.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  17. XM_046919813.1 → XP_046775769.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  18. XM_046919820.1 → XP_046775776.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  19. XM_046919828.1 → XP_046775784.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  20. XM_046919824.1 → XP_046775780.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  21. XM_046919811.1 → XP_046775767.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  22. XM_046919819.1 → XP_046775775.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94

  23. XM_046919826.1 → XP_046775782.1  phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1

    UniProtKB/TrEMBL
    F1DS94
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7T3T4.2 GenPept UniProtKB/Swiss-Prot:Q7T3T4

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