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slc37a4b solute carrier family 37 member 4b [ Danio rerio (zebrafish) ]

Gene ID: 393914, updated on 4-Jan-2025

Summary

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Official Symbol
slc37a4bprovided by ZNC
Official Full Name
solute carrier family 37 member 4bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-827
See related
Ensembl:ENSDARG00000077180 AllianceGenome:ZFIN:ZDB-GENE-040426-827
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
G6pt1; slc37a4; zgc:55871
Summary
Predicted to enable glucose 6-phosphate:phosphate antiporter activity. Predicted to be involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Predicted to be active in endoplasmic reticulum membrane. Is expressed in myotome. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II; glycogen storage disease Ib; and glycogen storage disease Ic. Orthologous to human SLC37A4 (solute carrier family 37 member 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See slc37a4b in Genome Data Viewer
Location:
chromosome: 10
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (39136106..39154603, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (39192826..39211399, complement)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene mitochondrial intermediate peptidase b Neighboring gene DNA ligase 1-like Neighboring gene ribosomal protein S25 Neighboring gene beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b Neighboring gene beta-galactosidase-1-like protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Characterization of genetic loss-of-function of Fus in zebrafish. Lebedeva S, et al. RNA Biol, 2017 Jan 2. PMID 27898262, Free PMC Article
  2. Gene expression profiling in zebrafish embryos exposed to diclofenac, an environmental toxicant. De Felice B, et al. Mol Biol Rep, 2012 Mar. PMID 21643954
  3. Functional characterization of zebrafish orthologs of the human Beta 3-Glucosyltransferase B3GLCT gene mutated in Peters Plus Syndrome. Weh E, et al. PLoS One, 2017. PMID 28926587, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC55871

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables glucose 6-phosphate:phosphate antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in glucose-6-phosphate transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphate ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
glucose-6-phosphate exchanger SLC37A4b
Names
solute carrier family 37 (glucose-6-phosphate transporter), member 4
solute carrier family 37 (glucose-6-phosphate transporter), member 4b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001328095.1 → NP_001315024.1  glucose-6-phosphate exchanger SLC37A4b

    Status: PROVISIONAL

    Source sequence(s)
    CU633908
    UniProtKB/TrEMBL
    A0A8M2BGJ1, F1QPV0
    Related
    ENSDARP00000097962.2, ENSDART00000111362.4
    Conserved Domains (1) summary
    cl27298
    Location:18 → 421
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    39136106..39154603 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169205.5 → XP_005169262.1  glucose-6-phosphate exchanger SLC37A4b isoform X1

    See identical proteins and their annotated locations for XP_005169262.1

    UniProtKB/TrEMBL
    A0A8M2BGJ1, F1QPV0
    Related
    ENSDARP00000151492.1, ENSDART00000186811.1
    Conserved Domains (1) summary
    cl27298
    Location:18 → 421
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]

  2. XM_021479139.2 → XP_021334814.1  glucose-6-phosphate exchanger SLC37A4b isoform X1

    UniProtKB/TrEMBL
    A0A8M2BGJ1, F1QPV0
    Conserved Domains (1) summary
    cl27298
    Location:18 → 421
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]
Nucleotide Protein Strain
Heading Accession and Version

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