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comm3 comm3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39696, updated on 9-Dec-2024

Summary

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Official Symbol
comm3provided by FlyBase
Official Full Name
comm3provided by FlyBase
Primary source
FLYBASE:FBgn0259236
Locus tag
Dmel_CG42334
See related
AllianceGenome:FB:FBgn0259236
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13446; CG13447; CG13448; CG33209; CG42334; Dmel\CG42334
Old locus tag
Dmel_CG13446; Dmel_CG33209
Summary
Predicted to be involved in axon guidance. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See comm3 in Genome Data Viewer
Location:
71E3-71E5; 3-43 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15613184..15647762, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15606284..15640862, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein at 71E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Phaser Neighboring gene long non-coding RNA:CR45977 Neighboring gene uncharacterized protein Neighboring gene Ecdysone-induced gene 71Ea

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comm sorts robo to control axon guidance at the Drosophila midline. Keleman K, et al. Cell, 2002 Aug 23. PMID 12202032
  2. The WAGR syndrome gene PRRG4 is a functional homologue of the commissureless axon guidance gene. Justice ED, et al. PLoS Genet, 2017 Aug. PMID 28859078, Free PMC Article
  3. Screening of suppressors of bax-induced cell death identifies glycerophosphate oxidase-1 as a mediator of debcl-induced apoptosis in Drosophila. Colin J, et al. Genes Cancer, 2015 May. PMID 26124923, Free PMC Article
  4. Genetic architecture of natural variation in visual senescence in Drosophila. Carbone MA, et al. Proc Natl Acad Sci U S A, 2016 Oct 25. PMID 27791033, Free PMC Article
  5. A SAGE approach to discovery of genes involved in autophagic cell death. Gorski SM, et al. Curr Biol, 2003 Feb 18. PMID 12593804

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
comm3
Names
CG42334-PC
CG42334-PD
CG42334-PE
comm3-PC
comm3-PD
comm3-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    15613184..15647762 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140534.3 → NP_648791.2  comm3, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648791.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q29QI2, Q9VUS2
    Conserved Domains (1) summary
    pfam15957
    Location:69 → 202
    Comm; Commissureless

  2. NM_001300143.1 → NP_001287072.1  comm3, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287072.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V6T5, Q9VUS1
    Conserved Domains (1) summary
    pfam15957
    Location:144 → 247
    Comm; Commissureless

  3. NM_176331.2 → NP_788509.1  comm3, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788509.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V6T5, Q9VUS1
    Related
    FBpp0289129
    Conserved Domains (1) summary
    pfam15957
    Location:144 → 247
    Comm; Commissureless
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2XY92 Q2XY92
Q9VUS1 Q9VUS1
Q9VUS2 Q9VUS2

Gene LinkOut

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