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Mes2 Mesoderm-expressed 2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40514, updated on 9-Dec-2024

Summary

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Official Symbol
Mes2provided by FlyBase
Official Full Name
Mesoderm-expressed 2provided by FlyBase
Primary source
FLYBASE:FBgn0037207
Locus tag
Dmel_CG11100
See related
AllianceGenome:FB:FBgn0037207
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
adfR; CG11100; Dmel\CG11100; mes-2; mes2; MES2
Summary
Involved in ecdysis, chitin-based cuticle and instar larval development. Located in nucleus. Is expressed in several structures, including endoderm anlage; glial cell; head epidermis primordium; mesoderm; and visceral mesoderm derivative. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Mes2 in Genome Data Viewer
Location:
80C1-80C1; 3-47 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (22945657..22952248)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (22938757..22945348)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene mir-9388 stem loop Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45758

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Promoter elements associated with RNA Pol II stalling in the Drosophila embryo. Hendrix DA, et al. Proc Natl Acad Sci U S A, 2008 Jun 3. PMID 18505835, Free PMC Article
  2. I-KCKT allows dissection-free RNA profiling of adult Drosophila intestinal progenitor cells. Buddika K, et al. Development, 2021 Jan 7. PMID 33246929, Free PMC Article
  3. Synchronous and stochastic patterns of gene activation in the Drosophila embryo. Boettiger AN, et al. Science, 2009 Jul 24. PMID 19628867, Free PMC Article
  4. PIF-like transposons are common in drosophila and have been repeatedly domesticated to generate new host genes. Casola C, et al. Mol Biol Evol, 2007 Aug. PMID 17556756
  5. Developmental Robustness: The Haltere Case in Drosophila. Giraud G, et al. Front Cell Dev Biol, 2021. PMID 34368162, Free PMC Article

See all (48) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in ecdysis, chitin-based cuticle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in instar larval development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of transcription regulator complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Mesoderm-expressed 2
Names
CG11100-PB
CG11100-PC
Mes2-PB
Mes2-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    22945657..22952248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168979.4 → NP_730768.1  Mesoderm-expressed 2, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730768.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VNP3
    Related
    FBpp0078212
    Conserved Domains (1) summary
    smart00595
    Location:62 → 149
    MADF; subfamily of SANT domain

  2. NM_168980.2 → NP_730769.2  Mesoderm-expressed 2, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730769.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IG95, Q8IPS2
    Related
    FBpp0078214
    Conserved Domains (1) summary
    smart00595
    Location:1 → 84
    MADF; subfamily of SANT domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IG95 Q8IG95
Q95ST8 Q95ST8
Q9VNP3 Q9VNP3

Gene LinkOut

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