ARHGAP6 Rho GTPase activating protein 6 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: ARHGAP6provided by CGNC
Official Full Name: Rho GTPase activating protein 6provided by CGNC
Primary source: CGNC:12440
See related: Ensembl:ENSGALG00010001966
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (124187135..124496537)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (124131590..124436454)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: rho GTPase-activating protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

124187135..124496537

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_416840.8 → XP_416840.5 rho GTPase-activating protein 6 isoform X1

Conserved Domains (2) summary

PHA03247
Location:27 → 153

PHA03247; large tegument protein UL36; Provisional

cd04376
Location:368 → 574

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662377.2 → XP_040518311.1 rho GTPase-activating protein 6 isoform X3

Conserved Domains (1) summary

cd04376
Location:239 → 445

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662387.2 → XP_040518321.1 rho GTPase-activating protein 6 isoform X4

Conserved Domains (1) summary

cd04376
Location:221 → 427

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662372.1 → XP_040518306.1 rho GTPase-activating protein 6 isoform X2

UniProtKB/TrEMBL

A0A8V0XDQ1

Related

ENSGALP00010002727.1, ENSGALT00010004483.1

Conserved Domains (1) summary

cd04376
Location:257 → 463

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662392.1 → XP_040518326.1 rho GTPase-activating protein 6 isoform X5

Conserved Domains (1) summary

cd04376
Location:208 → 414

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_046909394.1 → XP_046765350.1 rho GTPase-activating protein 6 isoform X6
XM_046909395.1 → XP_046765351.1 rho GTPase-activating protein 6 isoform X6
XM_040662409.2 → XP_040518343.1 rho GTPase-activating protein 6 isoform X6

Conserved Domains (1) summary

cd04376
Location:199 → 405

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662398.2 → XP_040518332.1 rho GTPase-activating protein 6 isoform X6

Conserved Domains (1) summary

cd04376
Location:199 → 405

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662416.2 → XP_040518350.1 rho GTPase-activating protein 6 isoform X6

Conserved Domains (1) summary

cd04376
Location:199 → 405

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

124131590..124436454

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040662256.2 → XP_040518190.1 rho GTPase-activating protein 6 isoform X1

Conserved Domains (2) summary

PHA03247
Location:27 → 153

PHA03247; large tegument protein UL36; Provisional

cd04376
Location:368 → 574

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662259.2 → XP_040518193.1 rho GTPase-activating protein 6 isoform X3

Conserved Domains (1) summary

cd04376
Location:239 → 445

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662260.2 → XP_040518194.1 rho GTPase-activating protein 6 isoform X4

Conserved Domains (1) summary

cd04376
Location:221 → 427

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662257.2 → XP_040518191.1 rho GTPase-activating protein 6 isoform X2

Conserved Domains (1) summary

cd04376
Location:257 → 463

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662261.2 → XP_040518195.1 rho GTPase-activating protein 6 isoform X5

Conserved Domains (1) summary

cd04376
Location:208 → 414

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_046908806.1 → XP_046764762.1 rho GTPase-activating protein 6 isoform X6
XM_046908807.1 → XP_046764763.1 rho GTPase-activating protein 6 isoform X6
XM_040662263.2 → XP_040518197.1 rho GTPase-activating protein 6 isoform X6

Conserved Domains (1) summary

cd04376
Location:199 → 405

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662262.2 → XP_040518196.1 rho GTPase-activating protein 6 isoform X6

Conserved Domains (1) summary

cd04376
Location:199 → 405

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...
XM_040662264.2 → XP_040518198.1 rho GTPase-activating protein 6 isoform X6

Conserved Domains (1) summary

cd04376
Location:199 → 405

RhoGAP_ARHGAP6; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS) ...