dan distal antenna [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: danprovided by FlyBase
Official Full Name: distal antennaprovided by FlyBase
Primary source: FLYBASE:FBgn0039286
Locus tag: Dmel_CG11849
See related: AllianceGenome:FB:FBgn0039286
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG11849; Dan; Dmel\CG11849; fer
Summary: Enables DNA-binding transcription factor activity. Involved in several processes, including antennal development; central nervous system formation; and segment specification. Located in nucleus. Is expressed in several structures, including anlage in statu nascendi; head epidermis primordium; imaginal disc; segment of antenna; and somatic precursor cell. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (25184383..25192806)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (21010105..21018528)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Dan forms condensates in neuroblasts and regulates nuclear architecture and progenitor competence in vivo.
Title: Dan forms condensates in neuroblasts and regulates nuclear architecture and progenitor competence in vivo.
Dan/Danr and Svp act in parallel pathways to limit Hb expression and allow neuroblasts to transition from making early-born neurons to late-born neurons at the proper time.
Title: The pipsqueak-domain proteins Distal antenna and Distal antenna-related restrict Hunchback neuroblast expression and early-born neuronal identity.
Dan and Danr have roles in Drosophila eye development
Title: distal antenna and distal antenna-related function in the retinal determination network during eye development in Drosophila.
fernandez and hernandez genes are required in the nervous system during the embryonic development
Title: Expression analysis of the Drosophila pipsqueak family members fernández/distal antenna and hernández/distal antenna related.
results show that the hernandez and fernandez genes are required for antennal and eye development and are also able to specify eye or antenna ectopically
Title: The hernandez and fernandez genes of Drosophila specify eye and antenna.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in antennal development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in central nervous system formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in compound eye development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of DNA-templated transcription	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in segment specification	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

Names: CG11849-PA; CG11849-PB; CG11849-PC; dan-PA; dan-PB; dan-PC; fernandez; tintin

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The following sections contain reference sequences that belong to a specific genome build. Explain