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Odf2l outer dense fiber of sperm tails 2-like [ Mus musculus (house mouse) ]

Gene ID: 52184, updated on 27-Nov-2024

Summary

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Official Symbol
Odf2lprovided by MGI
Official Full Name
outer dense fiber of sperm tails 2-likeprovided by MGI
Primary source
MGI:MGI:1098600
See related
Ensembl:ENSMUSG00000028256 AllianceGenome:MGI:1098600
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D3Ertd250e; 4733401D09Rik; 9630045K08Rik
Summary
Involved in negative regulation of cilium assembly. Predicted to be located in centriolar satellite. Predicted to be active in centrosome and ciliary basal body. Orthologous to human ODF2L (outer dense fiber of sperm tails 2 like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 2.7), CNS E14 (RPKM 2.0) and 27 other tissues See more
Orthologs
human all
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Genomic context

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See Odf2l in Genome Data Viewer
Location:
3 H2; 3 69.36 cM
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (144824330..144859676)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (145118569..145153915)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_09190 Neighboring gene STARR-seq mESC enhancer starr_09191 Neighboring gene STARR-positive B cell enhancer ABC_E1637 Neighboring gene chloride channel accessory 2 Neighboring gene STARR-positive B cell enhancer mm9_chr3:144794197-144794498 Neighboring gene predicted gene, 40163 Neighboring gene collagen, type XXIV, alpha 1 Neighboring gene STARR-seq mESC enhancer starr_09192 Neighboring gene predicted gene, 35133 Neighboring gene STARR-seq mESC enhancer starr_09193 Neighboring gene STARR-seq mESC enhancer starr_09194 Neighboring gene STARR-seq mESC enhancer starr_09195 Neighboring gene STARR-seq mESC enhancer starr_09196 Neighboring gene STARR-seq mESC enhancer starr_09197 Neighboring gene zinc finger, HIT type 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BCAP is a centriolar satellite protein and inhibitor of ciliogenesis. de Saram P, et al. J Cell Sci, 2017 Oct 1. PMID 28775150
  2. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cell projection organization IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of cilium assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of cilium assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
  
located_in centriolar satellite ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in centriole IEA
Inferred from Electronic Annotation
more info
  
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
  
located_in ciliary basal body ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein BCAP
Names
basal body centriole-associated protein
outer dense fiber protein 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001162538.2 → NP_001156010.1  protein BCAP isoform 1

    See identical proteins and their annotated locations for NP_001156010.1

    Status: VALIDATED

    Source sequence(s)
    AC152400
    Consensus CDS
    CCDS51087.1
    UniProtKB/Swiss-Prot
    Q8CD32, Q8VDY5, Q9D478, Q9D647
    Related
    ENSMUSP00000096140.3, ENSMUST00000098538.9
    Conserved Domains (2) summary
    pfam01496
    Location:325 → 382
    V_ATPase_I; V-type ATPase 116kDa subunit family
    cl19511
    Location:480 → 603
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)

  2. NM_001162539.2 → NP_001156011.1  protein BCAP isoform 3

    See identical proteins and their annotated locations for NP_001156011.1

    Status: VALIDATED

    Source sequence(s)
    AC152400
    Consensus CDS
    CCDS51088.1
    UniProtKB/Swiss-Prot
    Q9D478
    Related
    ENSMUSP00000029920.9, ENSMUST00000029920.15
    Conserved Domains (2) summary
    COG1196
    Location:241 → 494
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:84 → 349
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  3. NM_001428793.1 → NP_001415722.1  protein BCAP isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC152400

  4. NM_001428794.1 → NP_001415723.1  protein BCAP isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC152400

  5. NM_001428795.1 → NP_001415724.1  protein BCAP isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC152400

  6. NM_001428796.1 → NP_001415725.1  protein BCAP isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC152400

  7. NM_001428797.1 → NP_001415726.1  protein BCAP isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC152400

  8. NM_001428798.1 → NP_001415727.1  protein BCAP isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC152400

  9. NM_025714.5 → NP_079990.2  protein BCAP isoform 2

    See identical proteins and their annotated locations for NP_079990.2

    Status: VALIDATED

    Source sequence(s)
    AC152400
    Consensus CDS
    CCDS17891.1
    UniProtKB/Swiss-Prot
    Q9D478
    Related
    ENSMUSP00000096141.3, ENSMUST00000098539.7
    Conserved Domains (2) summary
    COG1196
    Location:284 → 537
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:127 → 392
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    144824330..144859676
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030252679.1 → XP_030108539.1  protein BCAP isoform X4

    Conserved Domains (2) summary
    COG1196
    Location:284 → 537
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:127 → 392
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  2. XM_006501678.4 → XP_006501741.1  protein BCAP isoform X1

    See identical proteins and their annotated locations for XP_006501741.1

    Conserved Domains (2) summary
    PRK02224
    Location:247 → 655
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG1196
    Location:89 → 380
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  3. XM_030252680.1 → XP_030108540.1  protein BCAP isoform X4

    Related
    ENSMUSP00000101798.3, ENSMUST00000106192.9
    Conserved Domains (2) summary
    COG1196
    Location:284 → 537
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:127 → 392
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  4. XM_006501675.4 → XP_006501738.1  protein BCAP isoform X1

    See identical proteins and their annotated locations for XP_006501738.1

    Conserved Domains (2) summary
    PRK02224
    Location:247 → 655
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG1196
    Location:89 → 380
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  5. XM_030252678.2 → XP_030108538.1  protein BCAP isoform X3

    Conserved Domains (2) summary
    COG1196
    Location:284 → 563
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:127 → 392
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  6. XM_030252677.1 → XP_030108537.1  protein BCAP isoform X2

    Conserved Domains (1) summary
    COG1196
    Location:90 → 611
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  7. XM_036163160.1 → XP_036019053.1  protein BCAP isoform X7

    Conserved Domains (1) summary
    TIGR02168
    Location:127 → 392
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  8. XM_030252683.2 → XP_030108543.1  protein BCAP isoform X8

    Conserved Domains (1) summary
    TIGR02168
    Location:127 → 392
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  9. XM_030252676.2 → XP_030108536.1  protein BCAP isoform X2

    Conserved Domains (1) summary
    COG1196
    Location:90 → 611
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  10. XM_036163161.1 → XP_036019054.1  protein BCAP isoform X9

    Conserved Domains (1) summary
    COG1196
    Location:67 → 370
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  11. XM_036163158.1 → XP_036019051.1  protein BCAP isoform X5

    Conserved Domains (2) summary
    COG1196
    Location:241 → 494
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:84 → 349
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  12. XM_006501681.3 → XP_006501744.1  protein BCAP isoform X1

    See identical proteins and their annotated locations for XP_006501744.1

    Conserved Domains (2) summary
    PRK02224
    Location:247 → 655
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG1196
    Location:89 → 380
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  13. XM_036163155.1 → XP_036019048.1  protein BCAP isoform X2

    Conserved Domains (1) summary
    COG1196
    Location:90 → 611
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  14. XM_036163159.1 → XP_036019052.1  protein BCAP isoform X5

    Conserved Domains (2) summary
    COG1196
    Location:241 → 494
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:84 → 349
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  15. XM_030252682.2 → XP_030108542.1  protein BCAP isoform X5

    Conserved Domains (2) summary
    COG1196
    Location:241 → 494
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:84 → 349
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  16. XM_006501676.5 → XP_006501739.1  protein BCAP isoform X1

    See identical proteins and their annotated locations for XP_006501739.1

    Conserved Domains (2) summary
    PRK02224
    Location:247 → 655
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG1196
    Location:89 → 380
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  17. XM_036163157.1 → XP_036019050.1  protein BCAP isoform X4

    Conserved Domains (2) summary
    COG1196
    Location:284 → 537
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:127 → 392
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  18. XM_006501677.5 → XP_006501740.1  protein BCAP isoform X1

    See identical proteins and their annotated locations for XP_006501740.1

    Conserved Domains (2) summary
    PRK02224
    Location:247 → 655
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG1196
    Location:89 → 380
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  19. XM_006501680.5 → XP_006501743.1  protein BCAP isoform X1

    See identical proteins and their annotated locations for XP_006501743.1

    Conserved Domains (2) summary
    PRK02224
    Location:247 → 655
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG1196
    Location:89 → 380
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  20. XM_030252681.2 → XP_030108541.1  protein BCAP isoform X4

    Conserved Domains (2) summary
    COG1196
    Location:284 → 537
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:127 → 392
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  21. XM_006501683.4 → XP_006501746.1  protein BCAP isoform X1

    See identical proteins and their annotated locations for XP_006501746.1

    Conserved Domains (2) summary
    PRK02224
    Location:247 → 655
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG1196
    Location:89 → 380
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  22. XM_006501682.3 → XP_006501745.1  protein BCAP isoform X1

    See identical proteins and their annotated locations for XP_006501745.1

    Conserved Domains (2) summary
    PRK02224
    Location:247 → 655
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG1196
    Location:89 → 380
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  23. XM_036163156.1 → XP_036019049.1  protein BCAP isoform X2

    Conserved Domains (1) summary
    COG1196
    Location:90 → 611
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  24. XM_011240157.4 → XP_011238459.1  protein BCAP isoform X1

    See identical proteins and their annotated locations for XP_011238459.1

    Conserved Domains (2) summary
    PRK02224
    Location:247 → 655
    PRK02224; DNA double-strand break repair Rad50 ATPase
    COG1196
    Location:89 → 380
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  25. XM_017319643.1 → XP_017175132.1  protein BCAP isoform X2

    Conserved Domains (1) summary
    COG1196
    Location:90 → 611
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  26. XM_006501688.4 → XP_006501751.1  protein BCAP isoform X6

    Conserved Domains (1) summary
    PRK02224
    Location:73 → 481
    PRK02224; DNA double-strand break repair Rad50 ATPase

RNA

  1. XR_004941360.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D478.1 GenPept UniProtKB/Swiss-Prot:Q9D478

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