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irak1bp1 interleukin-1 receptor-associated kinase 1 binding protein 1 [ Danio rerio (zebrafish) ]

Gene ID: 553809, updated on 4-Jan-2025

Summary

Official Symbol
irak1bp1provided by ZNC
Official Full Name
interleukin-1 receptor-associated kinase 1 binding protein 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-272
See related
Ensembl:ENSDARG00000036903 AllianceGenome:ZFIN:ZDB-GENE-050522-272
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:112481
Summary
Predicted to act upstream of or within immune response and positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in cytoplasm and nucleus. Orthologous to human IRAK1BP1 (interleukin 1 receptor associated kinase 1 binding protein 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See irak1bp1 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (31245395..31248952)
105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (31318864..31322421)

Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene hormonally up-regulated neu tumor-associated kinase homolog A Neighboring gene uncharacterized LOC103909696 Neighboring gene T-box transcription factor 18 Neighboring gene si:dkey-261l7.2 Neighboring gene pleckstrin homology domain interacting protein

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Clone Names

  • MGC112481

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within immune response IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
interleukin-1 receptor-associated kinase 1-binding protein 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020771.1NP_001018607.1  interleukin-1 receptor-associated kinase 1-binding protein 1 homolog

    See identical proteins and their annotated locations for NP_001018607.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095828
    UniProtKB/Swiss-Prot
    Q501X6
    Related
    ENSDARP00000053587.4, ENSDART00000053588.5
    Conserved Domains (1) summary
    pfam04402
    Location:49190
    SIMPL; Protein of unknown function (DUF541)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007134.7 Reference GRCz11 Primary Assembly

    Range
    31245395..31248952
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395159.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    85541..89098
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)