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KLF4 Kruppel like factor 4 [ Gallus gallus (chicken) ]

Gene ID: 770254, updated on 17-Aug-2024

Summary

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Symbol
KLF4provided by CGNC
Full Name
Kruppel like factor 4provided by CGNC
Primary source
CGNC:28582
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See KLF4 in Genome Data Viewer
Location:
chromosome: Z
Exon count:
5
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (56393942..56398448, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (56393942..56398448, complement)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 462 Neighboring gene microRNA 6565 Neighboring gene RAD23 homolog B, nucleotide excision repair protein Neighboring gene uncharacterized LOC121108643 Neighboring gene uncharacterized LOC121108534 Neighboring gene uncharacterized LOC107052355

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. miR-7 regulates the apoptosis of chicken primary myoblasts through the KLF4 gene. Zhang X, et al. Br Poult Sci, 2022 Feb. PMID 34287083
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. miR-7 regulates the apoptosis of chicken primary myoblasts through the KLF4 gene.
    Title: miR-7 regulates the apoptosis of chicken primary myoblasts through the KLF4 gene.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
Krueppel-like factor 4
Names
Kruppel-like factor 4 (gut)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    56393942..56398448 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004949369.5 → XP_004949426.2  Krueppel-like factor 4 isoform X1

    Conserved Domains (3) summary
    smart00355
    Location:435 → 457
    ZnF_C2H2; zinc finger
    COG5048
    Location:382 → 437
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:377 → 399
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_046905543.1 → XP_046761499.1  Krueppel-like factor 4 isoform X2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    56393942..56398448 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046936072.1 → XP_046792028.1  Krueppel-like factor 4 isoform X1

  2. XM_046936073.1 → XP_046792029.1  Krueppel-like factor 4 isoform X2

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials