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PIP1;4 plasma membrane intrinsic protein 1;4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 827956, updated on 18-Sep-2024

Summary

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Official Symbol
PIP1;4
Official Full Name
plasma membrane intrinsic protein 1;4
Primary source
TAIR:AT4G00430
Locus tag
AT4G00430
See related
Araport:AT4G00430
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
A_IG005I10.2; A_IG005I10_2; F5I10.2; F5I10_2; PIP1E; plasma membrane intrinsic protein 1;4; PLASMA MEMBRANE INTRINSIC PROTEIN 1E; TMP-C; TRANSMEMBRANE PROTEIN C
Summary
a member of the plasma membrane intrinsic protein subfamily PIP1.
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Genomic context

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See PIP1;4 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
4
Sequence:
Chromosome: 4; NC_003075.7 (185285..187680, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene methyl-CPG-binding domain 3 Neighboring gene Double-stranded RNA-binding domain (DsRBD)-containing protein Neighboring gene GPI-anchored adhesin-like protein, putative (DUF3741) Neighboring gene miscRNA Neighboring gene RNA polymerase II transcription mediator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Plant Aquaporin AtPIP1;4 Links Apoplastic H2O2 Induction to Disease Immunity Pathways. Tian S, et al. Plant Physiol, 2016 Jul. PMID 26945050, Free PMC Article
  2. Harpin Hpa1 Interacts with Aquaporin PIP1;4 to Promote the Substrate Transport and Photosynthesis in Arabidopsis. Li L, et al. Sci Rep, 2015 Nov 26. PMID 26607179, Free PMC Article
  3. Plasma Membrane Aquaporin Members PIPs Act in Concert to Regulate Cold Acclimation and Freezing Tolerance Responses in Arabidopsis thaliana. Rahman A, et al. Plant Cell Physiol, 2020 Apr 1. PMID 31999343
  4. Overexpression of PIP2;5 aquaporin alleviates effects of low root temperature on cell hydraulic conductivity and growth in Arabidopsis. Lee SH, et al. Plant Physiol, 2012 May. PMID 22434042, Free PMC Article
  5. The complete set of genes encoding major intrinsic proteins in Arabidopsis provides a framework for a new nomenclature for major intrinsic proteins in plants. Johanson U, et al. Plant Physiol, 2001 Aug. PMID 11500536, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Plasma Membrane Aquaporin Members PIPs Act in Concert to Regulate Cold Acclimation and Freezing Tolerance Responses in Arabidopsis thaliana.
    Title: Plasma Membrane Aquaporin Members PIPs Act in Concert to Regulate Cold Acclimation and Freezing Tolerance Responses in Arabidopsis thaliana.
  2. PIP1;4 functions as an effective facilitator of H2O2 transport across plasma membranes and mediates the translocation of externally applied H2O2 from the apoplast to the cytoplasm.PIP1;4 links pathogen-induced apoplastic H2O2 to the systemic acquired resistance pathway.
    Title: Plant Aquaporin AtPIP1;4 Links Apoplastic H2O2 Induction to Disease Immunity Pathways.
  3. Arabidopsis AtPIP1;4 is a plasma membrane sensor of Hpa1 and plays a dual role in plasma membrane permeability of CO2 and H2O.
    Title: Harpin Hpa1 Interacts with Aquaporin PIP1;4 to Promote the Substrate Transport and Photosynthesis in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_116268.4
NM_202760.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables channel activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables water channel activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within response to water deprivation IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within water transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in plasma membrane HDA PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
plasma membrane intrinsic protein 1;4
NP_567178.1
  • plasma membrane intrinsic protein 1;4 (PIP1;4); FUNCTIONS IN: water channel activity; INVOLVED IN: response to water deprivation, transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 1B (TAIR:AT2G45960.1); Has 10702 Blast hits to 10683 proteins in 2216 species: Archae - 88; Bacteria - 5147; Metazoa - 1472; Fungi - 442; Plants - 2512; Viruses - 2; Other Eukaryotes - 1039 (source: NCBI BLink).
NP_974489.1
  • TRANSMEMBRANE PROTEIN C (TMP-C); FUNCTIONS IN: water channel activity; INVOLVED IN: response to water deprivation, transport; LOCATED IN: membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 1B (TAIR:AT2G45960.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    185285..187680 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_116268.4 → NP_567178.1  plasma membrane intrinsic protein 1;4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567178.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23059, O23829, Q39196
    UniProtKB/TrEMBL
    A0A178USZ7, A0A5S9XNK3, A0A7G2EV15
    Conserved Domains (1) summary
    pfam00230
    Location:45 → 274
    MIP; Major intrinsic protein

  2. NM_202760.2 → NP_974489.1  plasma membrane intrinsic protein 1;4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_974489.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4JHB6
    Conserved Domains (1) summary
    cl00200
    Location:45 → 209
    MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q39196.1

Gene LinkOut

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