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EOL2 ETO1-like 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 835968, updated on 18-Sep-2024

Summary

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Official Symbol
EOL2
Official Full Name
ETO1-like 2
Primary source
TAIR:AT5G58550
Locus tag
AT5G58550
See related
Araport:AT5G58550
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ETO1-like 2; MZN1.1
Summary
Encodes a paralog of ETO1, which is a negative regulator of ACS5 (a key enzyme in ethylene biosynthesis pathway). EOL2 also interacts with and inhibits the activity of ACS5.
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Genomic context

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See EOL2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Sequence:
Chromosome: 5; NC_003076.8 (23665295..23668886, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Glutaredoxin family protein Neighboring gene ncRNA Neighboring gene Protein kinase superfamily protein Neighboring gene Phosphatidate cytidylyltransferase family protein Neighboring gene uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ACC synthase and its cognate E3 ligase are inversely regulated by light. Yoon GM, et al. Plant Signal Behav, 2013. PMID 24065059, Free PMC Article
  2. Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein. Wang KL, et al. Nature, 2004 Apr 29. PMID 15118728
  3. The BTB ubiquitin ligases ETO1, EOL1 and EOL2 act collectively to regulate ethylene biosynthesis in Arabidopsis by controlling type-2 ACC synthase levels. Christians MJ, et al. Plant J, 2009 Jan. PMID 18808454, Free PMC Article
  4. 14-3-3 regulates 1-aminocyclopropane-1-carboxylate synthase protein turnover in Arabidopsis. Yoon GM, et al. Plant Cell, 2013 Mar. PMID 23512855, Free PMC Article
  5. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Treatment of etiolated Arabidopsis seedlings with light rapidly increases the stability of ACS5 protein and destabilizes the ETO1/EOLs proteins.
    Title: ACC synthase and its cognate E3 ligase are inversely regulated by light.
  2. ETO1, EOL1 and EOL2 work together to negatively regulate ethylene synthesis, by helping degrade type-2 ACC synthases.
    Title: The BTB ubiquitin ligases ETO1, EOL1 and EOL2 act collectively to regulate ethylene biosynthesis in Arabidopsis by controlling type-2 ACC synthase levels.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of ethylene biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within regulation of ethylene biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
ETO1-like 2
NP_200663.2
  • ETO1-like 2 (EOL2); FUNCTIONS IN: protein binding; INVOLVED IN: regulation of ethylene biosynthetic process; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), BTB/POZ fold (InterPro:IPR011333), BTB/POZ (InterPro:IPR013069), Tetratricopeptide repeat-containing (InterPro:IPR013026), BTB/POZ-like (InterPro:IPR000210), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: tetratricopeptide repeat (TPR)-containing protein (TAIR:AT3G51770.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    23665295..23668886 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_125241.5 → NP_200663.2  ETO1-like 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_200663.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4KF02, Q0WQF6, Q6PWY1, Q9LV01
    Conserved Domains (4) summary
    smart00225
    Location:208 → 303
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00006
    Location:739 → 766
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:739 → 770
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:739 → 798
    TPR_11; TPR repeat
Nucleotide Protein
Heading Accession and Version

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