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LSG1 putative GTPase LSG1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852779, updated on 9-Dec-2024

Summary

Official Symbol
LSG1
Official Full Name
putative GTPase LSG1
Primary source
SGD:S000003067
Locus tag
YGL099W
See related
AllianceGenome:SGD:S000003067; FungiDB:YGL099W; VEuPathDB:YGL099W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
KRE35
Summary
Enables mRNA binding activity. Involved in ribosomal large subunit assembly and ribosomal subunit export from nucleus. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Orthologous to human LSG1 (large 60S subunit nuclear export GTPase 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See LSG1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (314631..316553)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene 5'-deoxynucleotidase Neighboring gene Seh1p Neighboring gene ncRNA Neighboring gene SNAP receptor USE1

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables GTP binding  
enables GTPase activity  
enables GTPase activity  
enables GTPase activity PubMed 
enables hydrolase activity  
enables mRNA binding PubMed 
Component Evidence Code Pubs
located_in cytoplasm PubMed 
located_in cytoplasm  
located_in cytosol PubMed 
is_active_in cytosol  
part_of cytosolic large ribosomal subunit PubMed 
located_in mating projection tip PubMed 

General protein information

Preferred Names
putative GTPase LSG1
NP_011416.3
  • Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    314631..316553
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180964.3 → NP_011416.3  TPA: putative GTPase LSG1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011416.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VU46, P53145
    UniProtKB/TrEMBL
    G2WE00, N1P5E5
    Conserved Domains (2) summary
    cd01857
    Location:187 → 394
    HSR1_MMR1; A circularly permuted subfamily of the Ras GTPases
    COG1161
    Location:167 → 528
    RbgA; Ribosome biogenesis GTPase A [Translation, ribosomal structure and biogenesis]
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