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PA0011 lipid A biosynthesis lauroyl acyltransferase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 877921, updated on 11-Sep-2024

Summary

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Gene symbol
PA0011
Gene description
lipid A biosynthesis lauroyl acyltransferase
Locus tag
PA0011
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (14235..15122)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene glycine--tRNA ligase subunit beta Neighboring gene glycine--tRNA ligase subunit alpha Neighboring gene DNA-3-methyladenine glycosidase I Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pleiotropic effects of temperature-regulated 2-OH-lauroytransferase (PA0011) on Pseudomonas aeruginosa antibiotic resistance, virulence and type III secretion system. Wang B, et al. Microb Pathog, 2016 Feb. PMID 26596709
  2. Site-specific activity of the acyltransferases HtrB1 and HtrB2 in Pseudomonas aeruginosa lipid A biosynthesis. Hittle LE, et al. Pathog Dis, 2015 Nov. PMID 26223882, Free PMC Article
  3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The inactivation of PA0011 rendered increased antibiotic susceptibility and decreased virulence.
    Title: Pleiotropic effects of temperature-regulated 2-OH-lauroytransferase (PA0011) on Pseudomonas aeruginosa antibiotic resistance, virulence and type III secretion system.
  2. In this study, the authors were able to show that both PA0011 (htrB1) and PA3242 (htrB2) are responsible for site-specific modification of lipid A.
    Title: Site-specific activity of the acyltransferases HtrB1 and HtrB2 in Pseudomonas aeruginosa lipid A biosynthesis.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
lipid A biosynthesis lauroyl acyltransferase
NP_248701.1
  • 'Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)'

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    14235..15122
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_248701.1 lipid A biosynthesis lauroyl acyltransferase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_248701.1

    Status: PROVISIONAL

    Conserved Domains (1) summary
    PRK05645
    Location:1 → 295
    PRK05645; lysophospholipid acyltransferase
Nucleotide Protein
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