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    chil-27 GH18 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 188616, updated on 9-Dec-2024

    Summary

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    Official Symbol
    chil-27
    Official Full Name
    GH18 domain-containing protein
    Primary source
    WormBase:WBGene00011848
    Locus tag
    CELE_T19H5.3
    See related
    AllianceGenome:WB:WBGene00011848
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See chil-27 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (9477867..9479696)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene GH18 domain-containing protein Neighboring gene GH18 domain-containing protein Neighboring gene ncRNA Neighboring gene Knot1 domain-containing protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans. Gang SS, et al. PLoS Genet, 2022 Oct. PMID 36191002, Free PMC Article
    2. A PAX6-regulated receptor tyrosine kinase pairs with a pseudokinase to activate immune defense upon oomycete recognition in Caenorhabditis elegans. Drury F, et al. Proc Natl Acad Sci U S A, 2023 Sep 26. PMID 37725647, Free PMC Article
    3. Chemosensory Neurons Modulate the Response to Oomycete Recognition in Caenorhabditis elegans. Fasseas MK, et al. Cell Rep, 2021 Jan 12. PMID 33440164, Free PMC Article
    4. Proteasome inhibition triggers tissue-specific immune responses against different pathogens in C. elegans. Grover M, et al. PLoS Biol, 2024 Mar. PMID 38466732, Free PMC Article
    5. Natural Infection of C. elegans by an Oomycete Reveals a New Pathogen-Specific Immune Response. Osman GA, et al. Curr Biol, 2018 Feb 19. PMID 29398216

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GH18 domain-containing protein
    NP_496035.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9477867..9479696
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063634.2 → NP_496035.1  GH18 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496035.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22597
      Conserved Domains (2) summary
      pfam00704
      Location:89 → 228
      Glyco_hydro_18; Glycosyl hydrolases family 18
      cl10447
      Location:97 → 235
      GH18_chitinase-like; The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods. Chitinases have ...
    Nucleotide Protein
    Heading Accession and Version

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