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    AI5_BETA intron-encoded DNA endonuclease aI5 beta [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854599, updated on 4-Jan-2025

    Summary

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    Official Symbol
    AI5_BETA
    Official Full Name
    intron-encoded DNA endonuclease aI5 beta
    Primary source
    SGD:S000007266
    Locus tag
    Q0075
    See related
    AllianceGenome:SGD:S000007266; FungiDB:Q0075; VEuPathDB:Q0075
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C, substrain: FY1679)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable endonuclease activity. Predicted to be involved in intron homing. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See AI5_BETA in Genome Data Viewer
    Sequence:
    Chromosome: MT; NC_001224.1 (24156..25255)

    Chromosome MT - NC_001224.1Genomic Context describing neighboring genes Neighboring gene tRNA-Trp Neighboring gene intron-encoded DNA endonuclease aI5 alpha Neighboring gene cytochrome c oxidase subunit 1 Neighboring gene intron-encoded reverse transcriptase aI1 Neighboring gene intron-encoded reverse transcriptase aI2 Neighboring gene intron-encoded DNA endonuclease aI3 Neighboring gene intron-encoded DNA endonuclease aI4 Neighboring gene F1F0 ATP synthase subunit 8 Neighboring gene F1F0 ATP synthase subunit a

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001224.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A DExH/D-box protein coordinates the two steps of splicing in a group I intron. Bifano AL, et al. J Mol Biol, 2008 Nov 14. PMID 18789947, Free PMC Article
    2. Disruption of the yeast nuclear PET54 gene blocks excision of mitochondrial intron aI5 beta from pre-mRNA for cytochrome c oxidase subunit I. Valencik ML, et al. EMBO J, 1989 Dec 1. PMID 2555177, Free PMC Article
    3. The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae. Foury F, et al. FEBS Lett, 1998 Dec 4. PMID 9872396
    4. Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications. Nitika, et al. PLoS Biol, 2022 Oct. PMID 36269765, Free PMC Article
    5. Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. Batisse J, et al. J Biol Chem, 2009 Dec 11. PMID 19840948, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in intron homing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    intron-encoded DNA endonuclease aI5 beta
    NP_009311.2
    • hypothetical protein; encoded within an intron of the mitochondrial COX1 gene; translational initiation codon is predicted to be ATA rather than ATG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001224.1 Reference assembly

      Range
      24156..25255
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_009311.2 intron-encoded DNA endonuclease aI5 beta (mitochondrion) [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009311.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      A0A0A7NYD5, Q9ZZX0
      UniProtKB/TrEMBL
      A0A0H3WKF2
      Conserved Domains (1) summary
      pfam00961
      Location:201 → 300
      LAGLIDADG_1; LAGLIDADG endonuclease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZZX0.1

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