Replication interactions
Interaction |
Pubs |
Knockdown of spectrin, alpha, non-erythrocytic 1 (SPTAN1) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells |
PubMed
|
Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Envelope surface glycoprotein gp120
|
env
|
Tandem affinity purification and mass spectrometry analysis identify spectrin alpha chain (SPTAN1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
|
Gag-Pol
|
gag-pol
|
Tandem affinity purification and mass spectrometry analysis identify spectrin alpha chain (SPTAN1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
|
Nef
|
nef
|
Tandem affinity purification and mass spectrometry analysis identify spectrin alpha chain (SPTAN1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
|
Pr55(Gag)
|
gag
|
Tandem affinity purification and mass spectrometry analysis identify spectrin alpha chain (SPTAN1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
|
Rev
|
rev
|
HIV-1 Rev interacting protein, spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) (SPTAN1), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells |
PubMed
|
Vpr
|
vpr
|
HIV-1 Vpr upregulates SPTAN1 in HeLa cells within 12 hours of exposure |
PubMed
|
retropepsin
|
gag-pol
|
A number of focal adhesion plaque proteins are specifically cleaved by HIV-1 protease, including fimbrin, focal adhesion plaque kinase (FAK), talin, and, to a lesser extent, filamin, spectrin and fibronectin |
PubMed
|
Go to the HIV-1, Human Interaction Database