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    Zfp936 zinc finger protein 936 [ Mus musculus (house mouse) ]

    Gene ID: 668620, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp936provided by MGI
    Official Full Name
    zinc finger protein 936provided by MGI
    Primary source
    MGI:MGI:3642994
    See related
    Ensembl:ENSMUSG00000064194 AllianceGenome:MGI:3642994
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm9272; EG435970; EG668620; I1C0022H11Rik
    Summary
    Predicted to be involved in regulation of gene expression. Predicted to be active in nucleus. Orthologous to several human genes including ZNF117 (zinc finger protein 117); ZNF490 (zinc finger protein 490); and ZNF708 (zinc finger protein 708). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Zfp936 in Genome Data Viewer
    Location:
    7 B3; 7 28.25 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (42763590..42841533)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (43114166..43192109)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor, pseudogene 158 Neighboring gene ribosomal protein L18A, pseudogene 4 Neighboring gene predicted gene, 17768 Neighboring gene STARR-seq mESC enhancer starr_18756 Neighboring gene predicted gene, 53348 Neighboring gene STARR-seq mESC enhancer starr_18757 Neighboring gene zinc finger protein 120 pseudogene Neighboring gene STARR-seq mESC enhancer starr_18760 Neighboring gene expressed sequence EU599041 Neighboring gene STARR-seq mESC enhancer starr_18761 Neighboring gene predicted gene, 35588

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC76792

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 936

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034893.2 → NP_001030065.1  zinc finger protein 936

      See identical proteins and their annotated locations for NP_001030065.1

      Status: VALIDATED

      Source sequence(s)
      AC123045, AC167161
      Consensus CDS
      CCDS80709.1
      UniProtKB/TrEMBL
      Q3ULA8
      Related
      ENSMUSP00000143800.2, ENSMUST00000202535.4
      Conserved Domains (4) summary
      COG5048
      Location:76 → 420
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:235 → 255
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 44
      KRAB; KRAB box
      pfam13465
      Location:416 → 440
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      42763590..42841533
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242903.2 → XP_030098763.1  zinc finger protein 936 isoform X1

      UniProtKB/TrEMBL
      Q3ULA8
      Conserved Domains (4) summary
      COG5048
      Location:76 → 420
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:235 → 255
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 44
      KRAB; KRAB box
      pfam13465
      Location:416 → 440
      zf-H2C2_2; Zinc-finger double domain

    2. XM_030242904.1 → XP_030098764.1  zinc finger protein 936 isoform X2

      Related
      ENSMUSP00000072608.4, ENSMUST00000072829.4
      Conserved Domains (3) summary
      COG5048
      Location:44 → 388
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:203 → 223
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:384 → 408
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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