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    Fmo6 flavin containing monooxygenase 6 [ Mus musculus (house mouse) ]

    Gene ID: 226565, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fmo6provided by MGI
    Official Full Name
    flavin containing monooxygenase 6provided by MGI
    Primary source
    MGI:MGI:2681841
    See related
    Ensembl:ENSMUSG00000095576 AllianceGenome:MGI:2681841
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable N,N-dimethylaniline monooxygenase activity. Is expressed in olfactory epithelium. Orthologous to human FMO6P (flavin containing dimethylaniline monoxygenase 6, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Fmo6 in Genome Data Viewer
    Location:
    1 H2.1; 1 70.34 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (162744120..162765135, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (162916551..162937566, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32197 Neighboring gene flavin containing monooxygenase 2 Neighboring gene predicted gene, 32279 Neighboring gene flavin containing monooxygenase 3 Neighboring gene crumbs homolog 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Organization and evolution of the flavin-containing monooxygenase genes of human and mouse: identification of novel gene and pseudogene clusters. Hernandez D, et al. Pharmacogenetics, 2004 Feb. PMID 15077013
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables N,N-dimethylaniline monooxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    flavin containing monooxygenase 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001178038.1 → NP_001171509.1  flavin containing monooxygenase 6

      See identical proteins and their annotated locations for NP_001171509.1

      Status: VALIDATED

      Source sequence(s)
      AC117767
      Consensus CDS
      CCDS56650.1
      UniProtKB/TrEMBL
      J3QMN6
      Related
      ENSMUSP00000136378.2, ENSMUST00000178465.3
      Conserved Domains (1) summary
      pfam00743
      Location:2 → 532
      FMO-like; Flavin-binding monooxygenase-like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      162744120..162765135 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496778.1 → XP_006496841.1  flavin containing monooxygenase 6 isoform X1

      See identical proteins and their annotated locations for XP_006496841.1

      UniProtKB/TrEMBL
      J3QMN6
      Conserved Domains (1) summary
      pfam00743
      Location:2 → 532
      FMO-like; Flavin-binding monooxygenase-like
    Nucleotide Protein Strain
    Heading Accession and Version

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