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    gtr-1 G_PROTEIN_RECEP_F1_2 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180427, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gtr-1
    Official Full Name
    G_PROTEIN_RECEP_F1_2 domain-containing protein
    Primary source
    WormBase:WBGene00017779
    Locus tag
    CELE_F25E2.1
    See related
    AllianceGenome:WB:WBGene00017779
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in neurons and ventral nerve cord. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gtr-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    8
    Sequence:
    Chromosome: X; NC_003284.9 (802778..804269)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene RING-type domain-containing protein Neighboring gene AT hook Transcription Factor family Neighboring gene Abnormal cell migration protein 18-like fibronectin type I domain-containing protein Neighboring gene Acyl-CoA thioesterase II

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A neuronal GPCR is critical for the induction of the heat shock response in the nematode C. elegans. Maman M, et al. J Neurosci, 2013 Apr 3. PMID 23554491, Free PMC Article
    2. Induction of Protective Response Associated with Expressional Alterations in Neuronal G Protein-Coupled Receptors in Polystyrene Nanoparticle Exposed Caenorhabditis elegans. Yang Y, et al. Chem Res Toxicol, 2021 May 17. PMID 33650869
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    G_PROTEIN_RECEP_F1_2 domain-containing protein
    NP_508157.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      802778..804269
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075756.5 → NP_508157.1  G_PROTEIN_RECEP_F1_2 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508157.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19779
      Conserved Domains (2) summary
      cd14964
      Location:44 → 64
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:44 → 278
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version

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