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    msp-77 Major sperm protein 77/79 [ Caenorhabditis elegans ]

    Gene ID: 177844, updated on 9-Dec-2024

    Summary

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    Official Symbol
    msp-77
    Official Full Name
    Major sperm protein 77/79
    Primary source
    WormBase:WBGene00003464
    Locus tag
    CELE_F32B6.6
    See related
    AllianceGenome:WB:WBGene00003464
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in oocyte maturation; positive regulation of MAPK cascade; and positive regulation of smooth muscle contraction. Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Is expressed in gonad; oocyte; and sperm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See msp-77 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_003282.8 (9894631..9895014)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene SH2 domain-containing protein Neighboring gene Sperm-Specific family, class S Neighboring gene Sperm-specific class P protein 32 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A sperm cytoskeletal protein that signals oocyte meiotic maturation and ovulation. Miller MA, et al. Science, 2001 Mar 16. PMID 11251118
    2. Evidence for phosphorylation in the MSP cytoskeletal filaments of amoeboid spermatozoa. Fraire-Zamora JJ, et al. Int J Biochem Mol Biol, 2011. PMID 22003439, Free PMC Article
    3. Proteasomal ubiquitin receptor RPN-10 controls sex determination in Caenorhabditis elegans. Shimada M, et al. Mol Biol Cell, 2006 Dec. PMID 17050737, Free PMC Article
    4. Genomic organization of major sperm protein genes and pseudogenes in the nematode Caenorhabditis elegans. Ward S, et al. J Mol Biol, 1988 Jan 5. PMID 3351915
    5. Clustered organization of reproductive genes in the C. elegans genome. Miller MA, et al. Curr Biol, 2004 Jul 27. PMID 15268860

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in oocyte maturation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of MAPK cascade IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of smooth muscle contraction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in pseudopodium IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Major sperm protein 77/79
    NP_501781.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      9894631..9895014
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069380.5 → NP_501781.1  Major sperm protein 77/79 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501781.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9TVW5
      Conserved Domains (1) summary
      pfam00635
      Location:9 → 114
      Motile_Sperm; MSP (Major sperm protein) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9TVW5.3

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