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    twk-13 Potassium channel domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 192077, updated on 9-Dec-2024

    Summary

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    Official Symbol
    twk-13
    Official Full Name
    Potassium channel domain-containing protein
    Primary source
    WormBase:WBGene00006668
    Locus tag
    CELE_R04F11.4
    See related
    AllianceGenome:WB:WBGene00006668
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in cholinergic neurons and ventral cord neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See twk-13 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    17
    Sequence:
    Chromosome: V; NC_003283.11 (12320170..12337994, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DNA polymerase delta subunit 3 Neighboring gene Mitochondrial import inner membrane translocase subunit Tim29 Neighboring gene ATP synthase subunit e, mitochondrial Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Asn Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional transcriptomics of a migrating cell in Caenorhabditis elegans. Schwarz EM, et al. Proc Natl Acad Sci U S A, 2012 Oct 2. PMID 22991463, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables outward rectifier potassium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium ion leak channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in potassium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Potassium channel domain-containing protein
    NP_001122984.1
    • Confirmed by transcript evidence
    NP_001263868.1
    • Partially confirmed by transcript evidence
    NP_001263869.1
    • Partially confirmed by transcript evidence
    NP_506091.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12320170..12337994 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073690.10 → NP_506091.2  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506091.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21729
      Conserved Domains (2) summary
      pfam00520
      Location:365 → 406
      Ion_trans; Ion transport protein
      pfam07885
      Location:156 → 211
      Ion_trans_2; Ion channel

    2. NM_001276939.4 → NP_001263868.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263868.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8ESB6
      Conserved Domains (2) summary
      pfam00520
      Location:385 → 451
      Ion_trans; Ion transport protein
      pfam07885
      Location:201 → 256
      Ion_trans_2; Ion channel

    3. NM_001129512.4 → NP_001122984.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122984.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B0M0M8
      Conserved Domains (2) summary
      pfam00520
      Location:398 → 464
      Ion_trans; Ion transport protein
      pfam07885
      Location:214 → 269
      Ion_trans_2; Ion channel

    4. NM_001276940.3 → NP_001263869.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263869.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8F7Q8
      Conserved Domains (2) summary
      pfam00520
      Location:363 → 429
      Ion_trans; Ion transport protein
      pfam07885
      Location:179 → 234
      Ion_trans_2; Ion channel
    Nucleotide Protein
    Heading Accession and Version

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