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    SND3 Snd3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852403, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SND3
    Official Full Name
    Snd3p
    Primary source
    SGD:S000000310
    Locus tag
    YBR106W
    See related
    AllianceGenome:SGD:S000000310; FungiDB:YBR106W; VEuPathDB:YBR106W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    PHO88
    Summary
    Involved in protein maturation and protein targeting to ER. Located in endoplasmic reticulum and membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SND3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (452658..453224)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene organic acid transporter Neighboring gene glucose-induced degradation complex subunit VID24 Neighboring gene Iml3p Neighboring gene Aim3p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phosphate transporter mediated lipid accumulation in Saccharomyces cerevisiae under phosphate starvation conditions. James AW, et al. Bioresour Technol, 2014 Jan. PMID 24212129
    2. A genome-wide screen identifies yeast genes required for protection against or enhanced cytotoxicity of the antimalarial drug quinine. Dos Santos SC, et al. Mol Genet Genomics, 2011 Dec. PMID 21960436
    3. A putative membrane protein, Pho88p, involved in inorganic phosphate transport in Saccharomyces cerevisiae. Yompakdee C, et al. Mol Gen Genet, 1996 Jul 19. PMID 8709965
    4. Disruption in phosphate transport affects membrane lipid and lipid droplet homeostasis in Saccharomyces cerevisiae. Subitha M, et al. J Bioenerg Biomembr, 2020 Aug. PMID 32462239
    5. Interactions between chromosomal and nonchromosomal elements reveal missing heritability. Edwards MD, et al. Proc Natl Acad Sci U S A, 2014 May 27. PMID 24825890, Free PMC Article

    See all (88) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphate ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein targeting to ER IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein targeting to ER IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Snd3p
    NP_009664.1
    • Involved in SRP-independent protein targeting to the ER; component of an alternative ER-targeting pathway partially redundant with the GET pathway that can compensate for SRP loss; preference for substrates with downstream transmembrane domains; interacts with Snd1p, Env10p/Snd2p, and Sec61p-translocon subunits; role in establishing nucleus-vacuole junctions (NVJs) in high glucose; targeted to the NVJ during glucose starvation to facilitate expansion; role in phosphate transport with Pho86p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      452658..453224
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178454.1 → NP_009664.1  TPA: Snd3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009664.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQA5, P38264
      UniProtKB/TrEMBL
      A6ZL51, B3LN47, B5VE69, C7GUK4, D3UEJ9, G2W9B1, N1P857
      Conserved Domains (1) summary
      pfam10032
      Location:6 → 181
      Pho88; Phosphate transport (Pho88)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38264.1

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