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    aar2 U5 snRNP-associated protein Aar2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543611, updated on 18-Sep-2024

    Summary

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    Official Symbol
    aar2
    Official Full Name
    U5 snRNP-associated protein Aar2
    Primary source
    PomBase:SPAC3H5.04
    Locus tag
    SPOM_SPAC3H5.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See aar2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3436000..3438112, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA polymerase alpha catalytic subunit Neighboring gene ncRNA Neighboring gene 40S ribosomal protein uS11 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene kinesin-14 family minus-end directed microtubule motor Pkl1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Splicing of branchpoint-distant exons is promoted by Cactin, Tls1 and the ubiquitin-fold-activated Sde2. Anil AT, et al. Nucleic Acids Res, 2022 Sep 23. PMID 36095128, Free PMC Article
    2. Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10. Livesay SB, et al. Eukaryot Cell, 2013 Nov. PMID 24014766, Free PMC Article
    3. The histone variant H2A.Z promotes splicing of weak introns. Nissen KE, et al. Genes Dev, 2017 Apr 1. PMID 28446597, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spliceosomal tri-snRNP complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of U5 snRNP ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    part_of spliceosomal complex NAS
    Non-traceable Author Statement
    more info
    		  

    General protein information

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    Preferred Names
    U5 snRNP-associated protein Aar2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3436000..3438112 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019612.3 → NP_594188.1  U5 snRNP-associated protein Aar2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594188.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q6LA53
      Conserved Domains (3) summary
      cd13777
      Location:1 → 111
      Aar2_N; N-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
      cd13778
      Location:148 → 305
      Aar2_C; C-terminal domain of Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor
      pfam05282
      Location:14 → 298
      AAR2; AAR2 protein
    Nucleotide Protein
    Heading Accession and Version

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