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    ani1 FKBP-type peptidyl-prolyl cis-trans isomerase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539812, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ani1
    Official Full Name
    FKBP-type peptidyl-prolyl cis-trans isomerase
    Primary source
    PomBase:SPBC1347.02
    Locus tag
    SPOM_SPBC1347.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    fkbp39
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    Genomic context

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    See ani1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (4064520..4065960)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene GATOR2-SEACAT complex/COPII-coated vesicle component/nuclear pore outer ring WD repeat protein Sec13 Neighboring gene ncRNA Neighboring gene deoxycytidyl transferase Rev1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene sporulation specific PIL domain protein Meu14 Neighboring gene TIM22 inner membrane protein import complex subunit Tim54

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Prolyl isomerization of the CENP-A N-terminus regulates centromeric integrity in fission yeast. Tan HL, et al. Nucleic Acids Res, 2018 Feb 16. PMID 29194511, Free PMC Article
    2. The SH3 domains of two PCH family members cooperate in assembly of the Schizosaccharomyces pombe contractile ring. Roberts-Galbraith RH, et al. J Cell Biol, 2009 Jan 12. PMID 19139265, Free PMC Article
    3. Chromatin localization of nucleophosmin organizes ribosome biogenesis. Ugolini I, et al. Mol Cell, 2022 Dec 1. PMID 36423630, Free PMC Article
    4. Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase. Chen JS, et al. Mol Cell Proteomics, 2013 May. PMID 23297348, Free PMC Article
    5. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables histone chaperone activity ISM
    Inferred from Sequence Model
    more info
    		  
    enables molecular condensate scaffold activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables nucleosome binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables peptidyl-prolyl cis-trans isomerase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables peptidyl-prolyl cis-trans isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables rDNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in CENP-A containing chromatin assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    NOT involved_in nucleolar large rRNA transcription by RNA polymerase I IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in ribosomal large subunit biogenesis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in ribosomal small subunit biogenesis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleolar chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of preribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FKBP-type peptidyl-prolyl cis-trans isomerase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      4064520..4065960
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022618.3 → NP_596694.1  FKBP-type peptidyl-prolyl cis-trans isomerase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596694.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74191, Q9UTU5
      Conserved Domains (2) summary
      COG0545
      Location:201 → 361
      FkpA; FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones]
      pfam00254
      Location:272 → 358
      FKBP_C; FKBP-type peptidyl-prolyl cis-trans isomerase
    Nucleotide Protein
    Heading Accession and Version

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