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    CG32369 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38873, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32369provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052369
    Locus tag
    Dmel_CG32369
    See related
    AllianceGenome:FB:FBgn0052369
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13684; CG7388; Dmel\CG32369
    Summary
    Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Is expressed in embryonic/larval midgut primordium; gut section; larval visceral muscle cell; and longitudinal visceral muscle primordium. Orthologous to several human genes including LONRF1 (LON peptidase N-terminal domain and ring finger 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32369 in Genome Data Viewer
    Location:
    66A13-66A14; 3-21 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7777105..7809825, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7770205..7802925, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Henna Neighboring gene Clock Neighboring gene PAR-domain protein 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Notch cooperates with Lozenge/Runx to lock haemocytes into a differentiation programme. Terriente-Felix A, et al. Development, 2013 Feb. PMID 23325760, Free PMC Article
    2. Genome-wide identification of hypoxia-induced enhancer regions. Kamps-Hughes N, et al. PeerJ, 2015. PMID 26713262, Free PMC Article
    3. Transcriptome analysis of Drosophila melanogaster laboratory strains of different geographical origin after long-term laboratory maintenance. Zarubin M, et al. Ecol Evol, 2020 Jul. PMID 32760513, Free PMC Article
    4. A circular RNA-gawky-chromatin regulatory axis modulates stress-induced transcription. Su R, et al. Nucleic Acids Res, 2024 Apr 24. PMID 38416578, Free PMC Article
    5. RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides. Abruzzi KC, et al. PLoS Genet, 2017 Feb. PMID 28182648, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c7800761-7793767 mobile_element_type = transposon:297{}950

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32369-PA
    CG32369-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7777105..7809825 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259731.3 → NP_001246660.1  uncharacterized protein Dmel_CG32369, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246660.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IG83, Q9VSB2
      Conserved Domains (6) summary
      cd00162
      Location:687 → 729
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl19481
      Location:791 → 1005
      LON; Found in ATP-dependent protease La (LON)
      sd00006
      Location:350 → 378
      TPR; TPR repeat [structural motif]
      pfam02190
      Location:802 → 1001
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
      pfam13414
      Location:349 → 412
      TPR_11; TPR repeat
      cl17238
      Location:183 → 206
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

    2. NM_168232.3 → NP_729296.1  uncharacterized protein Dmel_CG32369, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729296.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IG83, Q9VSB2
      Related
      FBpp0076498
      Conserved Domains (6) summary
      cd00162
      Location:687 → 729
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl19481
      Location:791 → 1005
      LON; Found in ATP-dependent protease La (LON)
      sd00006
      Location:350 → 378
      TPR; TPR repeat [structural motif]
      pfam02190
      Location:802 → 1001
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
      pfam13414
      Location:349 → 412
      TPR_11; TPR repeat
      cl17238
      Location:183 → 206
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IG83 Q8IG83
    Q9VSB1 Q9VSB1
    Q9VSB2 Q9VSB2

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