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    rplJ 50S ribosomal subunit protein L10 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948490, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rplJ
    Official Full Name
    50S ribosomal subunit protein L10
    Primary source
    ECOCYC:EG10871
    Locus tag
    b3985
    See related
    ASAP:ABE-0013035
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3976
    Summary
    The L10 protein is a component of the 50S subunit of the ribosome and also regulates the expression of the L10 () operon at the posttranscriptional level. [More information is available at EcoCyc: EG10871].
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    Genomic context

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    Sequence:
    NC_000913.3 (4179996..4180493)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 50S ribosomal subunit protein L11 Neighboring gene 50S ribosomal subunit protein L1 Neighboring gene 50S ribosomal subunit protein L12 Neighboring gene RNA polymerase subunit beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In vivo and in vitro structural analysis of the rplJ mRNA leader of Escherichia coli. Protection by bound L10-L7/L12. Climie SC, et al. J Biol Chem, 1988 Oct 15. PMID 3049601
    2. Autogenous control: ribosomal protein L10-L12 complex binds to the leader sequence of its mRNA. Johnsen M, et al. EMBO J, 1982. PMID 6765237, Free PMC Article
    3. Post-transcriptional regulatory mutants in a ribosomal protein-RNA polymerase operon of E. coli. Fiil NP, et al. Cell, 1980 Apr. PMID 6991124
    4. Autogenous control of Escherichia coli ribosomal protein L10 synthesis in vitro. Brot N, et al. Proc Natl Acad Sci U S A, 1980 May. PMID 6994102, Free PMC Article
    5. RNA secondary structure and translation inhibition: analysis of mutants in the rplJ leader. Christensen T, et al. EMBO J, 1984 Jul. PMID 6378628, Free PMC Article

    See all (68) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. N-terminus verified by Edman degradation on mature peptide
      Title: The primary structure of protein L10 from Escherichia coli ribosomes.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    contributes_to GTPase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables large ribosomal subunit rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribosome binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in negative regulation of translation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    50S ribosomal subunit protein L10

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4179996..4180493
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418412.1 50S ribosomal subunit protein L10 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418412.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376WBS3, A0A5B9ABF2, W1X8N0
      Conserved Domains (1) summary
      PRK00099
      Location:3 → 164
      rplJ; 50S ribosomal protein L10; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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