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    YRM1 Yrm1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854343, updated on 9-Dec-2024

    Summary

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    Official Symbol
    YRM1
    Official Full Name
    Yrm1p
    Primary source
    SGD:S000005698
    Locus tag
    YOR172W
    See related
    AllianceGenome:SGD:S000005698; FungiDB:YOR172W; VEuPathDB:YOR172W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See YRM1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (654210..656570)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene glutamine--tRNA ligase Neighboring gene sphinganine kinase LCB4 Neighboring gene 5'-(N(7)-methyl 5'-triphosphoguanosine)-(mRNA) diphosphatase Neighboring gene Med4p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cross-talk between transcriptional regulators of multidrug resistance in Saccharomyces cerevisiae. Zhang X, et al. J Biol Chem, 2001 Mar 23. PMID 11134057
    2. Cross talk between sphingolipids and glycerophospholipids in the establishment of plasma membrane asymmetry. Kihara A, et al. Mol Biol Cell, 2004 Nov. PMID 15342785, Free PMC Article
    3. A large-scale analysis of autophagy-related gene expression identifies new regulators of autophagy. Bernard A, et al. Autophagy, 2015 Nov 2. PMID 26649943, Free PMC Article
    4. The Absence of the Transcription Factor Yrr1p, Identified from Comparative Genome Profiling, Increased Vanillin Tolerance Due to Enhancements of ABC Transporters Expressing, rRNA Processing and Ribosome Biogenesis in Saccharomyces cerevisiae. Wang X, et al. Front Microbiol, 2017. PMID 28360888, Free PMC Article
    5. Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon. Lucau-Danila A, et al. J Biol Chem, 2003 Dec 26. PMID 14512416

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Yrm1p
    NP_014815.3
    • Zinc finger transcription factor involved in multidrug resistance; Zn(2)-Cys(6) zinc finger transcription factor; activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      654210..656570
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183591.3 → NP_014815.3  TPA: Yrm1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014815.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2M8, E9PAH0, Q12340, Q6B2M3
      UniProtKB/TrEMBL
      A6ZP15, C8ZGT3, N1NYJ5
      Conserved Domains (2) summary
      cd12148
      Location:307 → 579
      fungal_TF_MHR; fungal transcription factor regulatory middle homology region
      smart00066
      Location:25 → 68
      GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12340.1

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