U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Arpc5 Actin-related protein 2/3 complex, subunit 5 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33444, updated on 9-Dec-2024

    Summary

    Official Symbol
    Arpc5provided by FlyBase
    Official Full Name
    Actin-related protein 2/3 complex, subunit 5provided by FlyBase
    Primary source
    FLYBASE:FBgn0031437
    Locus tag
    Dmel_CG9881
    See related
    AllianceGenome:FB:FBgn0031437
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    ArpC5; ARPC5; CG9881; Dmel\CG9881; p16; p16-arc; p16-ARC; P16-ARC
    Summary
    Predicted to enable actin filament binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in regulation of actin filament polymerization. Located in lamellipodium. Is expressed in organism. Used to study candidiasis. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human ARPC5 (actin related protein 2/3 complex subunit 5) and ARPC5L (actin related protein 2/3 complex subunit 5 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Arpc5 in Genome Data Viewer
    Location:
    23A1-23A1; 2-7 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2580292..2581423)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2580292..2581423)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Early boundary activity 2 Neighboring gene NADH dehydrogenase (ubiquinone) B17.2 subunit Neighboring gene Dynamin related protein 1 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44790

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables actin filament binding  
    enables structural constituent of cytoskeleton PubMed 
    Component Evidence Code Pubs
    part_of Arp2/3 protein complex  
    part_of Arp2/3 protein complex  
    part_of Arp2/3 protein complex PubMed 
    located_in actin cytoskeleton  
    is_active_in cytoplasm  
    located_in lamellipodium PubMed 

    General protein information

    Preferred Names
    Actin-related protein 2/3 complex, subunit 5
    Names
    Arpc5-PA
    Arpc5-PB
    CG9881-PA
    CG9881-PB
    p16-ARC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2580292..2581423
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273016.1 → NP_001259945.1  Actin-related protein 2/3 complex, subunit 5, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259945.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQD8
      Conserved Domains (1) summary
      pfam04699
      Location:9 → 147
      P16-Arc; ARP2/3 complex 16 kDa subunit (p16-Arc)
    2. NM_134849.3 → NP_608693.1  Actin-related protein 2/3 complex, subunit 5, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608693.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQD8
      Related
      FBpp0077378
      Conserved Domains (1) summary
      pfam04699
      Location:9 → 147
      P16-Arc; ARP2/3 complex 16 kDa subunit (p16-Arc)
    External link. Please review our privacy policy.