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    SHC1 Shc1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856832, updated on 9-Dec-2024

    Summary

    Official Symbol
    SHC1
    Official Full Name
    Shc1p
    Primary source
    SGD:S000000898
    Locus tag
    YER096W
    See related
    AllianceGenome:SGD:S000000898; FungiDB:YER096W; VEuPathDB:YER096W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables enzyme activator activity. Involved in ascospore formation and chitin biosynthetic process. Located in prospore membrane. Orthologous to human DELE1 (DAP3 binding cell death enhancer 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See SHC1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (351698..353236)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene proteasome core particle subunit beta 3 Neighboring gene recombinase RAD51 Neighboring gene tRNA-Glu Neighboring gene putative ubiquitin-specific protease UBP9

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables enzyme activator activity  
    enables enzyme activator activity PubMed 
    Process Evidence Code Pubs
    involved_in ascospore formation PubMed 
    involved_in cell wall organization  
    involved_in chitin biosynthetic process  
    involved_in chitin biosynthetic process PubMed 
    involved_in fungal-type cell wall organization  
    involved_in sporulation resulting in formation of a cellular spore  
    Component Evidence Code Pubs
    located_in cytoplasm  
    located_in membrane  
    located_in prospore membrane PubMed 

    General protein information

    Preferred Names
    Shc1p
    NP_011022.1
    • Sporulation-specific activator of Chs3p (chitin synthase III); required for the synthesis of the chitosan layer of ascospores; transcriptionally induced at alkaline pH; SHC1 has a paralog, SKT5, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      351698..353236
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178987.1 → NP_011022.1  TPA: Shc1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011022.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DM04, P39000
      UniProtKB/TrEMBL
      B3LRL5, C7GRT0, C8Z7B5
      Conserved Domains (3) summary
      smart00671
      Location:354 → 389
      SEL1; Sel1-like repeats
      COG0790
      Location:304 → 493
      TPR; TPR repeat [Signal transduction mechanisms]
      sd00010
      Location:302 → 330
      SLR; SLR repeat [structural motif]
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