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    sano serrano [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37185, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sanoprovided by FlyBase
    Official Full Name
    serranoprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034408
    Locus tag
    Dmel_CG12758
    See related
    AllianceGenome:FB:FBgn0034408
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12758; Dmel\CG12758
    Summary
    Involved in establishment of ommatidial planar polarity and regulation of tube length, open tracheal system. Located in apical cortex. Is expressed in several structures, including clypeo-labral primordium; embryonic head epidermis; epidermis; gut section; and larval external sense organ gustatory receptor neurons. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See sano in Genome Data Viewer
    Location:
    55F8-56A1; 2-86 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18878391..18959500)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14765896..14847005)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Diptericin A Neighboring gene Diptericin B Neighboring gene Vacuolar H[+] ATPase 100kD subunit 3 Neighboring gene uncharacterized protein Neighboring gene proliferation disrupter

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. High-NaCl perception in Drosophila melanogaster. Alves G, et al. J Neurosci, 2014 Aug 13. PMID 25122890, Free PMC Article
    2. Alcohol sensitivity in Drosophila: translational potential of systems genetics. Morozova TV, et al. Genetics, 2009 Oct. PMID 19652175, Free PMC Article
    3. Genome-Wide Association Study on Male Genital Shape and Size in Drosophila melanogaster. Takahara B, et al. PLoS One, 2015. PMID 26182199, Free PMC Article
    4. Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior. Shorter J, et al. Proc Natl Acad Sci U S A, 2015 Jul 7. PMID 26100892, Free PMC Article
    5. Deficiency screening for genomic regions with effects on environmental sensitivity of the sensory bristles of Drosophila melanogaster. Takahashi KH, et al. Evolution, 2012 Sep. PMID 22946809

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in establishment of ommatidial planar polarity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of tube length, open tracheal system IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serrano
    Names
    CG12758-PA
    CG12758-PB
    CG12758-PC
    CG12758-PD
    CG12758-PE
    CG12758-PF
    sano-PA
    sano-PB
    sano-PC
    sano-PD
    sano-PE
    sano-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18878391..18959500
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166315.3 → NP_725839.1  serrano, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725839.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NLM8, Q965D9
      Related
      FBpp0085750
      Conserved Domains (1) summary
      pfam12736
      Location:31 → 267
      CABIT; Cell-cycle sustaining, positive selection,

    2. NM_001144234.2 → NP_001137706.1  serrano, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137706.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NLM8, Q965D9
      Conserved Domains (1) summary
      pfam12736
      Location:31 → 267
      CABIT; Cell-cycle sustaining, positive selection,

    3. NM_166314.3 → NP_725838.1  serrano, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725838.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NLM8, Q965D9
      Related
      FBpp0085751
      Conserved Domains (1) summary
      pfam12736
      Location:31 → 267
      CABIT; Cell-cycle sustaining, positive selection,

    4. NM_166316.3 → NP_725840.1  serrano, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725840.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NLM8, Q965D9
      Related
      FBpp0085752
      Conserved Domains (1) summary
      pfam12736
      Location:31 → 267
      CABIT; Cell-cycle sustaining, positive selection,

    5. NM_079064.4 → NP_523788.2  serrano, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523788.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NLM8, Q965D9
      Related
      FBpp0085753
      Conserved Domains (1) summary
      pfam12736
      Location:31 → 267
      CABIT; Cell-cycle sustaining, positive selection,

    6. NM_001299666.1 → NP_001286595.1  serrano, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286595.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LFU3, Q965D9
      Conserved Domains (1) summary
      pfam12736
      Location:164 → 400
      CABIT; Cell-cycle sustaining, positive selection,
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LFU3 A0A0B4LFU3
    Q6NLM8 Q6NLM8
    Q8MRR2 Q8MRR2
    Q965D9 Q965D9

    Gene LinkOut

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    Other Literature Sources
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