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    sfc4 transcription factor TFIIIC subunit Sfc4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539187, updated on 18-Sep-2024

    Summary

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    Official Symbol
    sfc4
    Official Full Name
    transcription factor TFIIIC subunit Sfc4
    Primary source
    PomBase:SPCC16C4.14c
    Locus tag
    SPOM_SPCC16C4.14C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See sfc4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (691825..694934, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 60S ribosomal protein uL11 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein uL2m

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A role for TFIIIC transcription factor complex in genome organization. Noma K, et al. Cell, 2006 Jun 2. PMID 16751097
    2. The Fun30 chromatin remodeler Fft3 controls nuclear organization and chromatin structure of insulators and subtelomeres in fission yeast. Steglich B, et al. PLoS Genet, 2015 Mar. PMID 25798942, Free PMC Article
    3. Isolation and cloning of four subunits of a fission yeast TFIIIC complex that includes an ortholog of the human regulatory protein TFIIICbeta. Huang Y, et al. J Biol Chem, 2000 Oct 6. PMID 10906331
    4. tRNA production links nutrient conditions to the onset of sexual differentiation through the TORC1 pathway. Otsubo Y, et al. EMBO Rep, 2018 Mar. PMID 29330317, Free PMC Article
    5. Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes. Iwasaki O, et al. Mol Cell, 2015 Sep 3. PMID 26257282, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA polymerase III general transcription initiation factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to chromatin insulator sequence binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase III promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    part_of transcription factor TFIIIC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIIIC complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor TFIIIC subunit Sfc4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      691825..694934 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022915.3 → NP_587924.1  transcription factor TFIIIC subunit Sfc4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587924.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74458
      Conserved Domains (2) summary
      sd00006
      Location:434 → 459
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:131 → 202
      TPR_11; TPR repeat
    Nucleotide Protein
    Heading Accession and Version

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