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    rad57 DNA recombination mediator, RecA family ATPase Rad57/Rhp57 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542007, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rad57
    Official Full Name
    DNA recombination mediator, RecA family ATPase Rad57/Rhp57
    Primary source
    PomBase:SPAC20H4.07
    Locus tag
    SPOM_SPAC20H4.07
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    rhp57
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    Genomic context

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    See rad57 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (2123030..2124506)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Gpl1-Gih35-Wdr83 complex RNA-binding subunit Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene phosphatase activator Neighboring gene ncRNA Neighboring gene ATP-dependent RNA helicase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of the rlp1+, the novel Rad51 paralog in the fission yeast Schizosaccharomyces pombe. Khasanov FK, et al. DNA Repair (Amst), 2004 Oct 5. PMID 15336631
    2. A recombination repair gene of Schizosaccharomyces pombe, rhp57, is a functional homolog of the Saccharomyces cerevisiae RAD57 gene and is phylogenetically related to the human XRCC3 gene. Tsutsui Y, et al. Genetics, 2000 Apr. PMID 10747044, Free PMC Article
    3. The role of novel genes rrp1(+) and rrp2(+) in the repair of DNA damage in Schizosaccharomyces pombe. Dziadkowiec D, et al. DNA Repair (Amst), 2009 May 1. PMID 19185548
    4. Crossover invariance determined by partner choice for meiotic DNA break repair. Hyppa RW, et al. Cell, 2010 Jul 23. PMID 20655467, Free PMC Article
    5. Five RecA-like proteins of Schizosaccharomyces pombe are involved in meiotic recombination. Grishchuk AL, et al. Genetics, 2003 Nov. PMID 14668362, Free PMC Article

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. rqh1 plays a role late in HR following replication arrest and Rhp55/57 has a postsynaptic function
      Title: A postsynaptic role for Rhp55/57 that is responsible for cell death in Deltarqh1 mutants following replication arrest in Schizosaccharomyces pombe.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity NAS
    Non-traceable Author Statement
    more info
    		  
    enables ATP-dependent DNA damage sensor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent activity, acting on DNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA strand exchange activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA recombinase assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA recombinase assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in DNA strand invasion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in double-strand break repair via homologous recombination IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in mating type switching IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in reciprocal meiotic recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Rad51C-XRCC3 complex NAS
    Non-traceable Author Statement
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in site of double-strand break IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA recombination mediator, RecA family ATPase Rad57/Rhp57

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2123030..2124506
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019058.3 → NP_593627.1  DNA recombination mediator, RecA family ATPase Rad57/Rhp57 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593627.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P7A6, Q9UUL2
      Conserved Domains (2) summary
      COG0468
      Location:32 → 354
      RecA; RecA/RadA recombinase [Replication, recombination and repair]
      cd01123
      Location:75 → 352
      Rad51_DMC1_radA; Rad51_DMC1_radA,B. This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal proteins radA and radB. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a ...
    Nucleotide Protein
    Heading Accession and Version

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