U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    sfmbt1 Scm like with four mbt domains 1 [ Danio rerio (zebrafish) ]

    Gene ID: 100001629, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    sfmbt1provided by ZNC
    Official Full Name
    Scm like with four mbt domains 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-2592
    See related
    Ensembl:ENSDARG00000109830 AllianceGenome:ZFIN:ZDB-GENE-030131-2592
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fc12f05
    Summary
    Predicted to enable histone binding activity and transcription corepressor activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in telencephalon. Orthologous to human SFMBT1 (Scm like with four mbt domains 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See sfmbt1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (18287064..18328429, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (18116175..18166513, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene musculoskeletal, embryonic nuclear protein 1b Neighboring gene uncharacterized LOC563780 Neighboring gene STIM activating enhance Neighboring gene protein kinase C, delta b Neighboring gene FYVE, RhoGEF and PH domain containing 5a

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    2. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    scm-like with four MBT domains protein 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      18287064..18328429 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021479792.2 → XP_021335467.1  scm-like with four MBT domains protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PVD7
      Conserved Domains (4) summary
      cd09581
      Location:784 → 868
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:22 → 120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:511 → 626
      SLED; SLED domain
      cl17705
      Location:153 → 234
      MBT; mbt repeat

    2. XM_021479793.2 → XP_021335468.1  scm-like with four MBT domains protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q7M7
      Conserved Domains (4) summary
      cd09581
      Location:783 → 867
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:22 → 120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:510 → 625
      SLED; SLED domain
      cl17705
      Location:153 → 234
      MBT; mbt repeat

    3. XM_021479791.2 → XP_021335466.1  scm-like with four MBT domains protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PVD7
      Related
      ENSDARP00000154520.1, ENSDART00000182590.1
      Conserved Domains (4) summary
      cd09581
      Location:784 → 868
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:22 → 120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:511 → 626
      SLED; SLED domain
      cl17705
      Location:153 → 234
      MBT; mbt repeat

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394814.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      210412..252007 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021472473.2 → XP_021328148.1  scm-like with four MBT domains protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PM68
      Conserved Domains (4) summary
      cd09581
      Location:784 → 868
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:22 → 120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:511 → 626
      SLED; SLED domain
      cl17705
      Location:153 → 234
      MBT; mbt repeat

    2. XM_003199480.6 → XP_003199528.2  scm-like with four MBT domains protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M1RSV3, F1QE28
      Conserved Domains (4) summary
      cd09581
      Location:783 → 867
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:22 → 120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:510 → 625
      SLED; SLED domain
      cl17705
      Location:153 → 234
      MBT; mbt repeat

    3. XM_005155839.5 → XP_005155896.2  scm-like with four MBT domains protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PM68
      Conserved Domains (4) summary
      cd09581
      Location:784 → 868
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:22 → 120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:511 → 626
      SLED; SLED domain
      cl17705
      Location:153 → 234
      MBT; mbt repeat
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools