U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SWP1 dolichyl-diphosphooligosaccharide-protein glycotransferase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855180, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SWP1
    Official Full Name
    dolichyl-diphosphooligosaccharide-protein glycotransferase
    Primary source
    SGD:S000004757
    Locus tag
    YMR149W
    See related
    AllianceGenome:SGD:S000004757; FungiDB:YMR149W; VEuPathDB:YMR149W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables structural molecule activity. Involved in protein N-linked glycosylation. Part of oligosaccharyltransferase complex. Is active in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SWP1 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (560996..561856)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene translation initiation factor eIF3 subunit i Neighboring gene Ldo45p Neighboring gene Ldo16p Neighboring gene endopeptidase catalytic subunit IMP1 Neighboring gene Yim1p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Sulfhydryl modification of the yeast Wbp1p inhibits oligosaccharyl transferase activity. Pathak R, et al. Biochemistry, 1995 Apr 4. PMID 7703229
    2. Yeast Wbp1p and Swp1p form a protein complex essential for oligosaccharyl transferase activity. te Heesen S, et al. EMBO J, 1993 Jan. PMID 8428586, Free PMC Article
    3. The essential OST2 gene encodes the 16-kD subunit of the yeast oligosaccharyltransferase, a highly conserved protein expressed in diverse eukaryotic organisms. Silberstein S, et al. J Cell Biol, 1995 Oct. PMID 7593165, Free PMC Article
    4. Heterologous expression and biophysical characterization of soluble oligosaccharyl transferase subunits. Dempski RE Jr, et al. Arch Biochem Biophys, 2004 Nov 1. PMID 15464727
    5. The alpha subunit of the Saccharomyces cerevisiae oligosaccharyltransferase complex is essential for vegetative growth of yeast and is homologous to mammalian ribophorin I. Silberstein S, et al. J Cell Biol, 1995 Feb. PMID 7860628, Free PMC Article

    See all (66) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural molecule activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein N-linked glycosylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein N-linked glycosylation IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of oligosaccharyltransferase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of oligosaccharyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of oligosaccharyltransferase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    dolichyl-diphosphooligosaccharide-protein glycotransferase
    NP_013869.1
    • Delta subunit of the oligosaccharyl transferase glycoprotein complex; complex is required for N-linked glycosylation of proteins in the endoplasmic reticulum

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      560996..561856
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182651.1 → NP_013869.1  TPA: dolichyl-diphosphooligosaccharide-protein glycotransferase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013869.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZX1, Q02795
      UniProtKB/TrEMBL
      A6ZMK8, G2WKK0
      Conserved Domains (2) summary
      PRK09401
      Location:83 → 163
      PRK09401; reverse gyrase; Reviewed
      pfam05817
      Location:156 → 282
      Ribophorin_II; Oligosaccharyltransferase subunit Ribophorin II
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q02795.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools