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    CG9945 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37329, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9945provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034527
    Locus tag
    Dmel_CG9945
    See related
    AllianceGenome:FB:FBgn0034527
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9945
    Summary
    Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Is expressed in organism. Orthologous to human DCAF11 (DDB1 and CUL4 associated factor 11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9945 in Genome Data Viewer
    Location:
    57A7-57A7; 2-91 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20618503..20621081)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16506008..16508586)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Heterogeneous nuclear ribonucleoprotein K Neighboring gene mir-7 stem loop Neighboring gene Hillarin Neighboring gene uncharacterized protein Neighboring gene Family with sequence similarity 21 Neighboring gene Reduction in Cnn dots 6 Neighboring gene uncharacterized protein Neighboring gene rigor mortis

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An RNAi screen identifies additional members of the Drosophila Integrator complex and a requirement for cyclin C/Cdk8 in snRNA 3'-end formation. Chen J, et al. RNA, 2012 Dec. PMID 23097424, Free PMC Article
    2. The tobacco phosphatidylethanolamine-binding protein NtFT4 increases the lifespan of Drosophila melanogaster by interacting with the proteostasis network. Känel P, et al. Aging (Albany NY), 2022 Apr 8. PMID 35396341, Free PMC Article
    3. p53 directs focused genomic responses in Drosophila. Akdemir F, et al. Oncogene, 2007 Aug 9. PMID 17310982
    4. The functional domain grouping of microtubule associated proteins. Fisher KH, et al. Commun Integr Biol, 2008. PMID 19704789, Free PMC Article
    5. A microtubule interactome: complexes with roles in cell cycle and mitosis. Hughes JR, et al. PLoS Biol, 2008 Apr 22. PMID 18433294, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9945-PA
    CG9945-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      20618503..20621081
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137650.3 → NP_611494.1  uncharacterized protein Dmel_CG9945, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611494.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JYQ4
      Related
      FBpp0085540
      Conserved Domains (3) summary
      COG2319
      Location:133 → 478
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:131 → 170
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:128 → 467
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_166403.2 → NP_725981.1  uncharacterized protein Dmel_CG9945, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725981.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JYQ4
      Related
      FBpp0085539
      Conserved Domains (3) summary
      COG2319
      Location:133 → 478
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:131 → 170
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:128 → 467
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JYQ4 Q7JYQ4

    Gene LinkOut

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