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    CG2930 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31341, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2930provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028491
    Locus tag
    Dmel_CG2930
    See related
    AllianceGenome:FB:FBgn0028491
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH06717; CG32780; CG32787; Dmel\CG2930
    Summary
    Predicted to enable dipeptide transmembrane transporter activity. Predicted to be involved in dipeptide import across plasma membrane. Predicted to be located in membrane. Predicted to be active in apical plasma membrane. Is expressed in adult head. Orthologous to several human genes including SLC15A1 (solute carrier family 15 member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2930 in Genome Data Viewer
    Location:
    3F4-3F4; 1-5 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (3868973..3880379)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (3763006..3774412)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene echinus Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA on the X 1 Neighboring gene yin Neighboring gene Vacuolar H[+] ATPase AC39 subunit 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional and bioinformatics analyses reveal conservation of cis-regulatory elements between sciaridae and drosophilidae. Lecci MS, et al. Genesis, 2008 Jan. PMID 18196600
    2. Oligopeptide Transporters of the SLC15 Family Are Dispensable for Peptidoglycan Sensing and Transport in Drosophila. Capo F, et al. J Innate Immun, 2017. PMID 28715804, Free PMC Article
    3. SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans. Paik D, et al. J Immunol, 2017 Jul 1. PMID 28539433, Free PMC Article
    4. A transcriptomics assessment of oxygen-temperature interactions reveals novel candidate genes underlying variation in thermal tolerance and survival. Boardman L, et al. J Insect Physiol, 2018 Apr. PMID 29038013
    5. Chromosome-wide gene-specific targeting of the Drosophila dosage compensation complex. Gilfillan GD, et al. Genes Dev, 2006 Apr 1. PMID 16547172, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables dipeptide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in dipeptide import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in oligopeptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2930-PA
    CG2930-PB
    CG2930-PD
    CG2930-PE
    CG2930-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      3868973..3880379
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001297917.1 → NP_001284846.1  uncharacterized protein Dmel_CG2930, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284846.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U4G9, Q9W4P6
      Conserved Domains (2) summary
      TIGR00926
      Location:140 → 771
      2A1704; Peptide:H+ symporter (also transports b-lactam antibiotics, the antitumor agent, bestatin, and various protease inhibitors)
      pfam00854
      Location:193 → 499
      PTR2; POT family

    2. NM_176682.2 → NP_788855.1  uncharacterized protein Dmel_CG2930, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788855.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IRT1
      Related
      FBpp0070581
      Conserved Domains (2) summary
      TIGR00926
      Location:140 → 773
      2A1704; Peptide:H+ symporter (also transports b-lactam antibiotics, the antitumor agent, bestatin, and various protease inhibitors)
      pfam00854
      Location:193 → 528
      PTR2; POT family

    3. NM_176684.3 → NP_788857.1  uncharacterized protein Dmel_CG2930, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788857.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U4G9, Q9W4P6
      Related
      FBpp0070583
      Conserved Domains (2) summary
      TIGR00926
      Location:140 → 771
      2A1704; Peptide:H+ symporter (also transports b-lactam antibiotics, the antitumor agent, bestatin, and various protease inhibitors)
      pfam00854
      Location:193 → 499
      PTR2; POT family

    4. NM_176683.3 → NP_788856.1  uncharacterized protein Dmel_CG2930, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788856.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U4G9, Q9W4P6
      Related
      FBpp0070582
      Conserved Domains (2) summary
      TIGR00926
      Location:140 → 771
      2A1704; Peptide:H+ symporter (also transports b-lactam antibiotics, the antitumor agent, bestatin, and various protease inhibitors)
      pfam00854
      Location:193 → 499
      PTR2; POT family

    5. NM_001297916.1 → NP_001284845.1  uncharacterized protein Dmel_CG2930, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284845.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U4G9, X2JCG8
      Conserved Domains (2) summary
      TIGR00926
      Location:145 → 776
      2A1704; Peptide:H+ symporter (also transports b-lactam antibiotics, the antitumor agent, bestatin, and various protease inhibitors)
      pfam00854
      Location:198 → 504
      PTR2; POT family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IRT1 Q8IRT1
    Q9U4G9 Q9U4G9
    Q9W4P6 Q9W4P6
    X2JCG8 X2JCG8

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