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    TYR1 prephenate dehydrogenase (NADP(+)) [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852464, updated on 9-Dec-2024

    Summary

    Official Symbol
    TYR1
    Official Full Name
    prephenate dehydrogenase (NADP(+))
    Primary source
    SGD:S000000370
    Locus tag
    YBR166C
    See related
    AllianceGenome:SGD:S000000370; FungiDB:YBR166C; VEuPathDB:YBR166C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables prephenate dehydrogenase (NAD+) activity. Involved in tyrosine biosynthetic process. Located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See TYR1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (569842..571200, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Arf family GTPase ARL1 Neighboring gene Ubs1p Neighboring gene ribonuclease P/MRP protein subunit POP7 Neighboring gene Pex32p

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables NAD+ binding  
    enables NADP binding  
    enables oxidoreductase activity  
    enables prephenate dehydrogenase (NAD+) activity  
    enables prephenate dehydrogenase (NAD+) activity PubMed 
    enables prephenate dehydrogenase (NAD+) activity  
    enables prephenate dehydrogenase (NAD+) activity PubMed 
    enables prephenate dehydrogenase (NADP+) activity  
    Component Evidence Code Pubs
    located_in cytoplasm PubMed 

    General protein information

    Preferred Names
    prephenate dehydrogenase (NADP(+))
    NP_009725.1
    • Prephenate dehydrogenase involved in tyrosine biosynthesis; expression is dependent on phenylalanine levels

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      569842..571200 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178514.1NP_009725.1  TPA: prephenate dehydrogenase (NADP(+)) [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009725.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQG2, P20049
      UniProtKB/TrEMBL
      G2W9G9, N1P8K9
      Conserved Domains (1) summary
      COG0287
      Location:11288
      TyrA; Prephenate dehydrogenase [Amino acid transport and metabolism]
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