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    CG2889 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31977, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2889provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030206
    Locus tag
    Dmel_CG2889
    See related
    AllianceGenome:FB:FBgn0030206
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2889
    Summary
    Predicted to enable DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2889 in Genome Data Viewer
    Location:
    9D1-9D1; 1-32 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10473938..10477201)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10367971..10371234)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Odorant receptor 9a Neighboring gene Neb-cGP Neighboring gene no circadian temperature entrainment Neighboring gene uncharacterized protein Neighboring gene Protein phosphatase 4 regulatory subunit 2-related protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Enhancer modeling uncovers transcriptional signatures of individual cardiac cell states in Drosophila. Busser BW, et al. Nucleic Acids Res, 2015 Feb 18. PMID 25609699, Free PMC Article
    2. An RNA-interference screen in Drosophila to identify ZAD-containing C2H2 zinc finger genes that function in female germ cells. Shapiro-Kulnane L, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561227, Free PMC Article
    3. ZAD-Domain Is Essential for Nuclear Localization of Insulator Proteins in Drosophila melanogaster. Zolotarev NA, et al. Acta Naturae, 2016 Jul-Sep. PMID 27795848, Free PMC Article
    4. Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila. Kasinathan B, et al. Elife, 2020 Nov 10. PMID 33169670, Free PMC Article
    5. Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. Brody T, et al. Mech Dev, 2002 Apr. PMID 11900973

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2889-PA
    CG2889-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10473938..10477201
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132404.2 → NP_572632.1  uncharacterized protein Dmel_CG2889, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572632.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2U6
      Related
      FBpp0071385
      Conserved Domains (2) summary
      sd00017
      Location:481 → 502
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:2 → 79
      zf-AD; Zinc-finger associated domain (zf-AD)

    2. NM_001258686.2 → NP_001245615.1  uncharacterized protein Dmel_CG2889, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245615.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2U6
      Conserved Domains (2) summary
      sd00017
      Location:481 → 502
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:2 → 79
      zf-AD; Zinc-finger associated domain (zf-AD)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W2U6 Q9W2U6

    Gene LinkOut

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