U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG12547 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3355145, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG12547provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0250830
    Locus tag
    Dmel_CG12547
    See related
    AllianceGenome:FB:FBgn0250830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Posey268; CG40277; Dmel\CG12547
    Summary
    Is expressed in adult head and organism. Orthologous to human NHLRC2 (NHL repeat containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG12547 in Genome Data Viewer
    Location:
    41C2-41C2; 2-55 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (4785855..4788965, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (673360..676470, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene conundrum Neighboring gene long non-coding RNA:CR46064 Neighboring gene pseudo Neighboring gene long non-coding RNA:CR46478 Neighboring gene long non-coding RNA:CR46476 Neighboring gene long non-coding RNA:CR46477

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Conundrum, an ARHGAP18 orthologue, regulates RhoA and proliferation through interactions with Moesin. Neisch AL, et al. Mol Biol Cell, 2013 May. PMID 23468526, Free PMC Article
    2. Genetic analysis of RpL38 and RpL5, two minute genes located in the centric heterochromatin of chromosome 2 of Drosophila melanogaster. Marygold SJ, et al. Genetics, 2005 Feb. PMID 15520262, Free PMC Article
    3. Genetic and bioinformatic analysis of 41C and the 2R heterochromatin of Drosophila melanogaster: a window on the heterochromatin-euchromatin junction. Myster SH, et al. Genetics, 2004 Feb. PMID 15020470, Free PMC Article
    4. Cytogenetic and molecular characterization of heterochromatin gene models in Drosophila melanogaster. Rossi F, et al. Genetics, 2007 Feb. PMID 17110485, Free PMC Article
    5. The paradox of functional heterochromatin. Dimitri P, et al. Bioessays, 2005 Jan. PMID 15612038

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG12547-PA
    CG12547-PB
    CG12547-PC
    anon-EST:Posey268

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      4785855..4788965 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273775.1 → NP_001260704.1  uncharacterized protein Dmel_CG12547, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260704.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W5T4
      Conserved Domains (4) summary
      cd03012
      Location:58 → 184
      TlpA_like_DipZ_like; TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA ...
      cd05819
      Location:227 → 271
      NHL; NHL repeat [structural motif]
      cd14951
      Location:262 → 618
      NHL-2_like; NHL repeat domain of NHL repeat-containing protein 2 and similar proteins
      cl18310
      Location:205 → 306
      NHL; NHL repeat unit of beta-propeller proteins

    2. NM_001299207.1 → NP_001286136.1  uncharacterized protein Dmel_CG12547, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286136.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LFP2
      Conserved Domains (4) summary
      cd05819
      Location:132 → 176
      NHL; NHL repeat [structural motif]
      cd14951
      Location:167 → 523
      NHL-2_like; NHL repeat domain of NHL repeat-containing protein 2 and similar proteins
      cl00388
      Location:1 → 89
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
      cl18310
      Location:110 → 211
      NHL; NHL repeat unit of beta-propeller proteins

    3. NM_001042995.2 → NP_001036460.1  uncharacterized protein Dmel_CG12547, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036460.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W5T4
      Conserved Domains (4) summary
      cd03012
      Location:58 → 184
      TlpA_like_DipZ_like; TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA ...
      cd05819
      Location:227 → 271
      NHL; NHL repeat [structural motif]
      cd14951
      Location:262 → 618
      NHL-2_like; NHL repeat domain of NHL repeat-containing protein 2 and similar proteins
      cl18310
      Location:205 → 306
      NHL; NHL repeat unit of beta-propeller proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LFP2 A0A0B4LFP2
    Q9W5T4 Q9W5T4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous