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    CG10165 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35242, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10165provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032801
    Locus tag
    Dmel_CG10165
    See related
    AllianceGenome:FB:FBgn0032801
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10165
    Summary
    Predicted to enable heme binding activity and transmembrane ascorbate ferrireductase activity. Orthologous to several human genes including CYB561D2 (cytochrome b561 family member D2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10165 in Genome Data Viewer
    Location:
    37E5-37E5; 2-54 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19526910..19530305, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19526910..19530305, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43363 Neighboring gene uncharacterized protein Neighboring gene Dolichyl-phosphate mannosyltransferase subunit 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45455

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparison of insect and human cytochrome b561 proteins: Insights into candidate ferric reductases in insects. Holst JD, et al. PLoS One, 2023. PMID 38039324, Free PMC Article
    2. Deficiency screening for genomic regions with effects on environmental sensitivity of the sensory bristles of Drosophila melanogaster. Takahashi KH, et al. Evolution, 2012 Sep. PMID 22946809
    3. Genomic response to selection for postponed senescence in Drosophila. Wilson RH, et al. Mech Ageing Dev, 2013 Mar. PMID 23262286, Free PMC Article
    4. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane ascorbate ferrireductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transmembrane monodehydroascorbate reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10165-PA
    CG10165-PB
    CG10165-PC
    CG10165-PD
    CG10165-PE
    NP_001188850.1
    NP_001188851.1
    NP_001286086.1
    NP_609982.1
    NP_724208.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      19526910..19530305 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001201921.2 → NP_001188850.1  uncharacterized protein Dmel_CG10165, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188850.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIU6
      Conserved Domains (1) summary
      pfam03188
      Location:47 → 182
      Cytochrom_B561; Eukaryotic cytochrome b561

    2. NM_136138.4 → NP_609982.1  uncharacterized protein Dmel_CG10165, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609982.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIU6
      Related
      FBpp0080815
      Conserved Domains (1) summary
      pfam03188
      Location:47 → 182
      Cytochrom_B561; Eukaryotic cytochrome b561

    3. NM_165309.3 → NP_724208.1  uncharacterized protein Dmel_CG10165, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724208.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIU6
      Related
      FBpp0080816
      Conserved Domains (1) summary
      pfam03188
      Location:47 → 182
      Cytochrom_B561; Eukaryotic cytochrome b561

    4. NM_001201922.2 → NP_001188851.1  uncharacterized protein Dmel_CG10165, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188851.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIU6
      Conserved Domains (1) summary
      pfam03188
      Location:47 → 182
      Cytochrom_B561; Eukaryotic cytochrome b561

    5. NM_001299157.1 → NP_001286086.1  uncharacterized protein Dmel_CG10165, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286086.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIU6
      Conserved Domains (1) summary
      pfam03188
      Location:47 → 182
      Cytochrom_B561; Eukaryotic cytochrome b561
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VIU6 Q9VIU6

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