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    rutF FMN reductase RutF [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946594, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rutF
    Official Full Name
    FMN reductase RutF
    Primary source
    ECOCYC:G6518
    Locus tag
    b1007
    See related
    ASAP:ABE-0003403
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0998; ycdH
    Summary
    NtrC regulon. [More information is available at EcoGene: EG13854]. Escherichia coli K-12 contains a previously undescribed pathway for pyrimidine degradation. [More information is available at EcoCyc: G6518].
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    Genomic context

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    Sequence:
    NC_000913.3 (1069860..1070354, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene stress-induced bacterial acidophilic repeat motifs-containing protein YmdF Neighboring gene pyrimidine:H(+) symporter Neighboring gene putative malonic semialdehyde reductase Neighboring gene putative aminoacrylate hydrolase RutD

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Catalysis of a flavoenzyme-mediated amide hydrolysis. Mukherjee T, et al. J Am Chem Soc, 2010 Apr 28. PMID 20369853, Free PMC Article
    2. Comparative genomics reveals novel biochemical pathways. Piskur J, et al. Trends Genet, 2007 Aug. PMID 17555842
    3. A hidden metabolic pathway exposed. Osterman A. Proc Natl Acad Sci U S A, 2006 Apr 11. PMID 16595627, Free PMC Article
    4. The Rut pathway for pyrimidine degradation: novel chemistry and toxicity problems. Kim KS, et al. J Bacteriol, 2010 Aug. PMID 20400551, Free PMC Article
    5. Nitrogen regulatory protein C-controlled genes of Escherichia coli: scavenging as a defense against nitrogen limitation. Zimmer DP, et al. Proc Natl Acad Sci U S A, 2000 Dec 19. PMID 11121068, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables FMN reductase (NAD(P)H) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables FMN reductase (NADH) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables FMN reductase (NADH) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables riboflavin reductase (NADPH) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables riboflavin reductase (NADPH) activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables riboflavin reductase (NADPH) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in nitrogen utilization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in nitrogen utilization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nitrogen utilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pyrimidine nucleobase catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within pyrimidine nucleobase catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in uracil catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in uracil catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within uracil catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FMN reductase RutF
    NP_415527.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1069860..1070354 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415527.4 FMN reductase RutF [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415527.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FL36
      Conserved Domains (1) summary
      TIGR03615
      Location:4 → 159
      RutF; pyrimidine utilization flavin reductase protein F
    Nucleotide Protein
    Heading Accession and Version

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