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    uhpC inner membrane protein sensing glucose-6-phosphate [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948184, updated on 17-Dec-2024

    Summary

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    Official Symbol
    uhpC
    Official Full Name
    inner membrane protein sensing glucose-6-phosphate
    Primary source
    ECOCYC:EG11053
    Locus tag
    b3667
    See related
    ASAP:ABE-0011990
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3658
    Summary
    UhpC transporter activity is not required for sensing. [More information is available at EcoGene: EG11053]. UhpC belongs to the phosphorelay system UhpB-UhpC-UhpA and is involved in the regulation of the uptake of hexose phosphates . [More information is available at EcoCyc: EG11053].
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    Genomic context

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    Sequence:
    NC_000913.3 (3847305..3848624, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene adenine deaminase Neighboring gene ncRNA Neighboring gene hexose-6-phosphate:phosphate antiporter Neighboring gene sensory histidine kinase UhpB Neighboring gene DNA-binding transcriptional activator UhpA Neighboring gene acetohydroxy acid synthase I subunit IlvN

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. uhp-directed, glucose 6-phosphate membrane receptor in Escherichia coli. Goldenbaum PE, et al. J Bacteriol, 1980 Apr. PMID 6989810, Free PMC Article
    2. Properties of the glucose-6-phosphate transporter from Chlamydia pneumoniae (HPTcp) and the glucose-6-phosphate sensor from Escherichia coli (UhpC). Schwöppe C, et al. J Bacteriol, 2002 Apr. PMID 11914341, Free PMC Article
    3. Glucose-6-phosphate transporter and receptor functions of the glucose 6-phosphatase system analyzed from a consensus defined by multiple alignments. Méchin MC, et al. Proteins, 2000 Nov 1. PMID 10966570
    4. The family of organo-phosphate transport proteins includes a transmembrane regulatory protein. Kadner RJ, et al. J Bioenerg Biomembr, 1993 Dec. PMID 8144492
    5. Promoter elements required for positive control of transcription of the Escherichia coli uhpT gene. Merkel TJ, et al. J Bacteriol, 1992 May. PMID 1569008, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables glucose 6-phosphate:phosphate antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glucose-6-phosphate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphate ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within phosphorelay signal transduction system EXP
    Inferred from Experiment
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphorelay signal transduction system IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    inner membrane protein sensing glucose-6-phosphate

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3847305..3848624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418123.2 inner membrane protein sensing glucose-6-phosphate [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418123.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1X3JAB3, A0AAN3SED0
      Conserved Domains (1) summary
      PRK11663
      Location:8 → 439
      PRK11663; glucose-6-phosphate receptor/MFS transporter UhpC
    Nucleotide Protein
    Heading Accession and Version

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