CG8468 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG8468provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0033913
Locus tag: Dmel_CG8468
See related: AllianceGenome:FB:FBgn0033913
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Dmel\CG8468
Summary: Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be active in plasma membrane. Is expressed in several structures, including Malpighian tubule primordium; adult head; anterior endoderm; embryonic/larval midgut primordium; and gut section. Orthologous to several human genes including SLC16A14 (solute carrier family 16 member 14) and SLC16A8 (solute carrier family 16 member 8). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 50E4-50E4; 2-69 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (14219898..14230620)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (10107403..10118125)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables monocarboxylic acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in monocarboxylic acid transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein

Names: CG8468-PA; CG8468-PB; CG8468-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033778.4 Reference assembly

Range

14219898..14230620

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_137096.3 → NP_610940.1 uncharacterized protein Dmel_CG8468, isoform B [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_610940.1

Status: REVIEWED

UniProtKB/TrEMBL

Q7K1L4

Related

FBpp0086663

Conserved Domains (1) summary

cd06174
Location:50 → 227

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
NM_166039.2 → NP_725368.1 uncharacterized protein Dmel_CG8468, isoform C [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_725368.1

Status: REVIEWED

UniProtKB/TrEMBL

Q7K1L4

Related

FBpp0086661

Conserved Domains (1) summary

cd06174
Location:50 → 227

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
NM_166038.2 → NP_725367.1 uncharacterized protein Dmel_CG8468, isoform A [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_725367.1

Status: REVIEWED

UniProtKB/TrEMBL

Q7K1L4

Related

FBpp0086662

Conserved Domains (1) summary

cd06174
Location:50 → 227

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...