Gbeta5 G protein beta subunit 5 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Gbeta5provided by FlyBase
Official Full Name: G protein beta subunit 5provided by FlyBase
Primary source: FLYBASE:FBgn0030011
Locus tag: Dmel_CG10763
See related: AllianceGenome:FB:FBgn0030011
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG10763; Dmel\CG10763; Gbeta; Gbeta 5; Gbetagamma; GNB5; G[[beta5]]; G[[beta]]
Summary: Predicted to enable signaling receptor complex adaptor activity. Predicted to be involved in G protein-coupled dopamine receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in cytoplasm. Is expressed in several structures, including embryonic central brain neurons; embryonic head sensory system; embryonic/larval midgut; ganglia; and organism subdivision. Human ortholog(s) of this gene implicated in intellectual developmental disorder with cardiac arrhythmia. Orthologous to human GNB5 (G protein subunit beta 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (8150731..8152275, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (8044764..8046308, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables signaling receptor complex adaptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G protein-coupled dopamine receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in G protein-coupled receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info
involved_in signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of heterotrimeric G-protein complex	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain