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    rpl-6 Large ribosomal subunit protein eL6 [ Caenorhabditis elegans ]

    Gene ID: 176015, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rpl-6
    Official Full Name
    Large ribosomal subunit protein eL6
    Primary source
    WormBase:WBGene00004417
    Locus tag
    CELE_R151.3
    See related
    AllianceGenome:WB:WBGene00004417
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in cytosol; ribosome; and rough endoplasmic reticulum. Predicted to be part of cytosolic large ribosomal subunit. Orthologous to human RPL6 (ribosomal protein L6). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rpl-6 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (7208447..7209789)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Zinc metalloproteinase dpy-31 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ribose-phosphate pyrophosphokinase 2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation of eight novel Caenorhabditis elegans small RNAs. Wachi M, et al. Gene, 2004 Jun 23. PMID 15194189
    2. Molecular phylogeny of beetle associated diplogastrid nematodes suggests host switching rather than nematode-beetle coevolution. Mayer WE, et al. BMC Evol Biol, 2009 Aug 24. PMID 19703296, Free PMC Article
    3. Direct and heterologous approaches to identify the LET-756/FGF interactome. Popovici C, et al. BMC Genomics, 2006 May 3. PMID 16672054, Free PMC Article
    4. rRNA intermediates coordinate the formation of nucleolar vacuoles in C. elegans. Xu D, et al. Cell Rep, 2023 Aug 29. PMID 37537842
    5. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Hansen M, et al. Aging Cell, 2007 Feb. PMID 17266679

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in determination of adult lifespan IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in rough endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Large ribosomal subunit protein eL6
    NP_498584.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      7208447..7209789
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066183.7 → NP_498584.1  Large ribosomal subunit protein eL6 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498584.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P47991
      Conserved Domains (2) summary
      COG2163
      Location:67 → 189
      RPL14A; Ribosomal protein L14E/L6E/L27E [Translation, ribosomal structure and biogenesis]
      cd13156
      Location:63 → 217
      KOW_RPL6; KOW motif of Ribosomal Protein L6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47991.1

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