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    SNR7-L [ Saccharomyces cerevisiae S288C ]

    Gene ID: 9164899, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SNR7-L
    Primary source
    SGD:S000006495
    Locus tag
    YNCG0044C
    See related
    AllianceGenome:SGD:S000006495
    Gene type
    ncRNA
    RNA name
    snRNA
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables pre-mRNA 5'-splice site binding activity. Contributes to second spliceosomal transesterification activity. Involved in alignment of 3' and 5' splice sites of mRNA. Part of U4/U6 x U5 tri-snRNP complex and U5 snRNP. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SNR7-L in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (939459..939672, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene mitochondrial 54S ribosomal protein YmL9 Neighboring gene Tos2p Neighboring gene ncRNA Neighboring gene Pet54p Neighboring gene Hsv2p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutations in yeast U5 snRNA alter the specificity of 5' splice-site cleavage. Newman A, et al. Cell, 1991 Apr 5. PMID 2013092
    2. Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8. Kershaw CJ, et al. RNA, 2009 Jul. PMID 19447917, Free PMC Article
    3. An essential yeast snRNA with a U5-like domain is required for splicing in vivo. Patterson B, et al. Cell, 1987 Jun 5. PMID 3555841
    4. Functional analysis of the U5 snRNA loop 1 in the second catalytic step of yeast pre-mRNA splicing. O'Keefe RT, et al. EMBO J, 1998 Jan 15. PMID 9430647, Free PMC Article
    5. Mutations in U5 snRNA loop 1 influence the splicing of different genes in vivo. O'Keefe RT. Nucleic Acids Res, 2002 Dec 15. PMID 12490716, Free PMC Article

    See all (55) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    • U5 spliceosomal RNA (U5 snRNA), long form; associated with spliceosome

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables pre-mRNA 5'-splice site binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    contributes_to second spliceosomal transesterification activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in alignment of 3' and 5' splice sites of mRNA IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in generation of catalytic spliceosome for second transesterification step IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA 5'-splice site recognition IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spliceosomal complex assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in spliceosomal tri-snRNP complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U4/U6 x U5 tri-snRNP complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U4/U6 x U5 tri-snRNP complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of U5 snRNP IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U5 snRNP IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      939459..939672 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. NR_132184.1 RNA Sequence

      Status: REVIEWED

    Gene LinkOut

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