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    mhpR DNA-binding transcriptional activator MhpR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945938, updated on 3-Dec-2024

    Summary

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    Official Symbol
    mhpR
    Official Full Name
    DNA-binding transcriptional activator MhpR
    Primary source
    ECOCYC:G6201
    Locus tag
    b0346
    See related
    ASAP:ABE-0001191
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0343
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    Genomic context

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    Sequence:
    NC_000913.3 (367587..368420, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene beta-galactosidase Neighboring gene DNA-binding transcriptional repressor LacI Neighboring gene 3-(3-hydroxyphenyl)propanoate hydroxylase Neighboring gene 3-carboxyethylcatechol 2,3-dioxygenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. 3-Hydroxyphenylpropionate and phenylpropionate are synergistic activators of the MhpR transcriptional regulator from Escherichia coli. Manso I, et al. J Biol Chem, 2009 Aug 7. PMID 19520845, Free PMC Article
    2. Regulation of the mhp cluster responsible for 3-(3-hydroxyphenyl)propionic acid degradation in Escherichia coli. Torres B, et al. J Biol Chem, 2003 Jul 25. PMID 12748194
    3. Isolation and characterization of Escherichia coli mutants defective for phenylpropionate degradation. Burlingame RP, et al. J Bacteriol, 1986 Oct. PMID 3531186, Free PMC Article
    4. Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12. Ferrández A, et al. J Bacteriol, 1997 Apr. PMID 9098055, Free PMC Article
    5. Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12. Díaz E, et al. J Bacteriol, 1998 Jun. PMID 9603882, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. 3-Hydroxyphenylpropionate and phenylpropionate are synergistic activators of the MhpR transcriptional regulator from Escherichia coli
      Title: 3-Hydroxyphenylpropionate and phenylpropionate are synergistic activators of the MhpR transcriptional regulator from Escherichia coli.
    2. N-terminus verified by Edman degradation on complete protein
      Title: Regulation of the mhp cluster responsible for 3-(3-hydroxyphenyl)propionic acid degradation in Escherichia coli.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional activator MhpR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      367587..368420 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414880.2 DNA-binding transcriptional activator MhpR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414880.2

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A140NF20
      Conserved Domains (1) summary
      PRK09834
      Location:7 → 268
      PRK09834; DNA-binding transcriptional regulator
    Nucleotide Protein
    Heading Accession and Version

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