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    yfaL putative autotransporter adhesin YfaL [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946595, updated on 3-Dec-2024

    Summary

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    Official Symbol
    yfaL
    Official Full Name
    putative autotransporter adhesin YfaL
    Primary source
    ECOCYC:EG12850
    Locus tag
    b2233
    See related
    ASAP:ABE-0007377
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2225; yfaF; yfaJ; yfaK
    Summary
    Apparently cleaved fragment that may be a C-terminal passenger domain has been observed in a Western blot (Marani, 2006). [More information is available at EcoGene: EG12850]. YfaL is a potential adhesin. [More information is available at EcoCyc: EG12850].
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    Genomic context

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    Sequence:
    NC_000913.3 (2340417..2344169, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA gyrase subunit A Neighboring gene bifunctional 3-demethylubiquinone-8 3-O-methyltransferase and 2-octaprenyl-6-hydroxyphenol methylase Neighboring gene protein YpaB Neighboring gene ribonucleoside-diphosphate reductase 1 subunit alpha

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biophysical insights into sugar-dependent medium acidification promoting YfaL protein-mediated Escherichia coli self-aggregation, biofilm formation and acid stress resistance. Chekli Y, et al. Nanoscale, 2024 Sep 26. PMID 39225712
    2. The parD- mutant of Escherichia coli also carries a gyrAam mutation. The complete sequence of gyrA. Hussain K, et al. Mol Microbiol, 1987 Nov. PMID 2834621
    3. Primary structure of the Escherichia coli ribonucleoside diphosphate reductase operon. Carlson J, et al. Proc Natl Acad Sci U S A, 1984 Jul. PMID 6087316, Free PMC Article
    4. Combined inactivation and expression strategy to study gene function under physiological conditions: application to identification of new Escherichia coli adhesins. Roux A, et al. J Bacteriol, 2005 Feb. PMID 15659678, Free PMC Article
    5. Fishing new proteins in the twilight zone of genomes: the test case of outer membrane proteins in Escherichia coli K12, Escherichia coli O157:H7, and other Gram-negative bacteria. Casadio R, et al. Protein Sci, 2003 Jun. PMID 12761386, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Biophysical insights into sugar-dependent medium acidification promoting YfaL protein-mediated Escherichia coli self-aggregation, biofilm formation and acid stress resistance.
      Title: Biophysical insights into sugar-dependent medium acidification promoting YfaL protein-mediated Escherichia coli self-aggregation, biofilm formation and acid stress resistance.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables serine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cell adhesion involved in single-species biofilm formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to UV IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative autotransporter adhesin YfaL

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2340417..2344169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416736.1 putative autotransporter adhesin YfaL [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416736.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7JM26
      Conserved Domains (1) summary
      PRK09752
      Location:1 → 1250
      PRK09752; AIDA-I family autotransporter YfaL
    Nucleotide Protein
    Heading Accession and Version

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